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Table 3 The 3-year survival rates of locally advanced NPC patients with different GTV-P and T categories

From: Prognostic value and predictive threshold of tumor volume for patients with locally advanced nasopharyngeal carcinoma receiving intensity-modulated radiotherapy

Variable OS (%) P value LRFS (%) P value DMFS (%) P value DFS (%) P value
GTV-P (mL)   <0.001   0.015   <0.001   <0.001
 ≤46.4 90.5   96.6   90.2   85.3  
 >46.4 75.5   90.9   74.5   67.5  
T category   0.105   0.667   0.035   0.033
 T3 89.6   93.2   93.2   88.1  
 T4 83.7   94.7   82.8   76.4  
Sub-T3a   0.345   0.158     
 T3V1 90.7   94.5   94.5   89.1  
 T3V2 75.0   75.0   75.0   75.0  
Sub-T4b   <0.001   0.014   <0.001   <0.001
 T4V1 90.4   97.2   89.4   84.0  
 T4V2 75.6   91.5   74.5   67.3  
  1. OS overall survival, LRFS local relapse-free survival, DMFS distant metastasis-free survival, DFS disease-free survival
  2. aT3 tumors were subclassified as T3V1 (T3 tumors with GTV-P ≤46.4 mL) and T3V2 tumors (T3 tumors with GTV-P >46.4 mL)
  3. bT4 tumors were subclassified as T4V1 (T4 tumors with GTV-P ≤46.4 mL) and T4V2 tumors (T4 tumors with GTV-P >46.4 mL)