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Table 2 Sensitivity, specificity, and AUC of different cut-off values of GTV-P for survival prediction in the 346 patients with locally advanced NPC

From: Prognostic value and predictive threshold of tumor volume for patients with locally advanced nasopharyngeal carcinoma receiving intensity-modulated radiotherapy

End-point GTV-P cut-off value
46.4 mL 57.9 mL 75.4 mL
Sensitivity (%) Specificity (%) AUC Sensitivity (%) Specificity (%) AUC Sensitivity (%) Specificity (%) AUC
OS 59.4 66 0.662 39.1 79.4 26.6 90.4
LRFS 50 62 62.5 77.9 0.702 25 88
DMFS 61.8 65.6 40 79.2 36.4 91.8 0.668
DFS 56.6 66.9 0.668 37.5 80.1 26.5 91.6
  1. Twelve patients were lost to follow-up and, thus, were not included in the survival analysis
  2. AUC area under the curve, OS overall survival, LRFS local relapse-free survival, DMFS distant metastasis-free survival, DFS disease-free survival
  3. – AUC of inferior cut-off value for the endpoint was not calculated