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Table 2 Sensitivity, specificity, and AUC of different cut-off values of GTV-P for survival prediction in the 346 patients with locally advanced NPC

From: Prognostic value and predictive threshold of tumor volume for patients with locally advanced nasopharyngeal carcinoma receiving intensity-modulated radiotherapy

End-point

GTV-P cut-off value

46.4 mL

57.9 mL

75.4 mL

Sensitivity (%)

Specificity (%)

AUC

Sensitivity (%)

Specificity (%)

AUC

Sensitivity (%)

Specificity (%)

AUC

OS

59.4

66

0.662

39.1

79.4

26.6

90.4

LRFS

50

62

62.5

77.9

0.702

25

88

DMFS

61.8

65.6

40

79.2

36.4

91.8

0.668

DFS

56.6

66.9

0.668

37.5

80.1

26.5

91.6

  1. Twelve patients were lost to follow-up and, thus, were not included in the survival analysis
  2. AUC area under the curve, OS overall survival, LRFS local relapse-free survival, DMFS distant metastasis-free survival, DFS disease-free survival
  3. – AUC of inferior cut-off value for the endpoint was not calculated