|
Variable
|
No. of cases
|
Median overall survival (months)
|
P*
|
|---|
|
Age (years)
| | |
0.080
|
|
<50
|
16
|
12
| |
|
≥50
|
18
|
27
| |
|
Sex
| | |
0.623
|
|
Men
|
30
|
14
| |
|
Women
|
4
|
22
| |
|
Tumor size (cm)
| | |
0.012
|
|
<3
|
9
|
29
| |
|
≥3
|
25
|
10
| |
|
HBsAg
| | |
0.660
|
|
Positive
|
32
|
14
| |
|
Negative
|
2
|
6
| |
|
Microvascular invasion of HCC
| |
1
|
0.019
|
|
Yes
|
17
|
0
| |
|
No
|
17
|
29
| |
|
Lymph node metastasis of ICC
| | |
<0.001
|
|
Yes
|
6
|
7
| |
|
No
|
28
|
22
| |
|
Cirrhosis
| | |
0.004
|
|
Yes
|
20
|
10
| |
|
No
|
14
|
29
| |
|
Serum AFP level (ng/mL)
|
|
<20 vs. ≥20
|
10 vs. 24
|
18 vs. 12
|
0.907
|
|
<1000 vs. ≥1000
|
22 vs. 12
|
18 vs. 10
|
0.311
|
|
Serum CA19–9 level (ng/mL)
|
|
<38 vs. ≥38
|
20 vs. 14
|
22 vs. 10
|
0.174
|
|
<100 vs. ≥100
|
30 vs. 4
|
22 vs. 14
|
0.958
|
|
Edmondson grade of HCC
| | |
0.847
|
|
I–II
|
4
|
8
| |
|
III–IV
|
30
|
18
| |
|
Histologic differentiation of ICC
| | |
<0.001
|
|
Well to moderate
|
24
|
27
| |
|
Poor
|
10
|
7
| |
-
HBsAg hepatitis B surface antigen, AFP ɑ-fetoprotein, CA19-9 carbohydrate antigen 19-9, HCC hepatocellular carcinoma, ICC intrahepatic cholangiocarcinoma
-
*Log-rank test
