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Table 2 Univariate analysis of different prognostic factors for survival in 335 patients with sHCC (Cox proportional hazards regression)

From: Prognostic factors affecting postoperative survival of patients with solitary small hepatocellular carcinoma

Variable Overall survival Recurrence-free survival
HR (95% CI) P value HR (95% CI) P value
Gender (male vs. female) 0.825 (0.374–1.816) 0.825 0.663 (0.366–1.202) 0.176
Age (>48 vs. ≤48 years) 1.014 (0.615–1.672) 0.331 1.171 (0.829–1.654) 0.371
ALT (≤40 vs. >40 U/L) 1.337 (0.812–2.201) 0.949 1.272 (0.902–1.795) 0.170
AFP (≤20 vs. >20 ng/mL) 1.230 (0.734–2.059) 0.130 0.912 (0.644–1.289) 0.601
Tumor size (≤2.5 vs. > 2.5 cm) 2.431 (1.443–4.093) 0.014 1.710 (1.211–2.415) 0.002
Tumor differentiation (well-moderate vs. poor-undifferentiated) 1.215 (0.679–2.175) 0.172 1.774 (1.221–2.578) 0.003
Vascular invasion (absent vs. present) 3.033 (1.827–5.035) 0.001 1.790 (1.236–2.594) 0.002
Envelope (absent vs. present) 0.920 (0.544–1.559) 0. 110 0.958 (0.668–1.375) 0. 816
Liver cirrhosis (absent vs. present) 1.516 (0.921–2.495) 0.496 1.329 (0.939–1.881) 0.108
  1. AFP alpha-fetoprotein, ALT alanine aminotranferease, HR hazards ratio, CI confidence interval
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