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Table 4 Comparison of frequency of various major complications of VHL syndrome across different cohorts

From: Clinical and molecular characteristics of East Asian patients with von Hippel–Lindau syndrome

Clinical manifestation

Present study

Ong et al. [18]

Maher et al. [4]

CNSH

81.2% (125/154)

Cerebellar 57%

Spinal 25%

Cerebellar 59%

Spinal 13%

RCH

27.9% (43/154)

73%

59%

RCC

57.8% (89/154)

35%

28%

PCC

14.9% (23/154)

20%

7%

  1. CNSH central nervous system hemangioblastoma, RCH retinal capillary hemangioblastoma, RCC renal cell carcinoma, PCC pheochromocytoma