Skip to main content

Table 4 Combined effects of miR-605 rs2043556 and miR-196a2 rs11614913 on oral squamous cell carcinoma (OSCC) risk

From: Association of microRNA polymorphisms with the risk of head and neck squamous cell carcinoma in a Chinese population: a case–control study

Number of risk allelesa Patients [number (%)] Controls [number (%)] Adjust OR (95% CI)b P b
0–1 66 (14.3) 303 (19.6) 1.00  
2 153 (33.2) 575 (37.2) 1.20 (0.87–1.66) 0.262
3 168 (36.4) 517 (33.4) 1.51 (1.102.09) 0.011
4 74 (16.1) 151 (9.8) 2.23 (1.513.29) <0.001
Trend NA NA 1.21 (1.101.32) <0.001
Binary classification     <0.001
 0–2 219 (47.5) 878 (56.8) 1.00
 3–4 242 (52.5) 668 (43.2) 1.48 (1.201.83)
  1. Italic value indicate significance of p value (p < 0.05)
  2. aThe miR-605 rs2043556 A and miR-196a2 rs11614913 G allele were assumed as risk alleles based on the main effect of the individual locus and were genotyped in the 461 OSCC cases and 1546 controls
  3. bAdjusted by age, sex, smoking status, and drinking status