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Table 2 Primary information and minor allele frequencies (MAFs) of selected single-nuclide polymorphisms (SNPs)

From: Association of microRNA polymorphisms with the risk of head and neck squamous cell carcinoma in a Chinese population: a case–control study

Gene

Chromosome

SNP

Base change

Call rates (%)

HWE

MAF in controls

P a

P b

Has-miR-149

2q37.3

rs2292832

A>G

99.77

0.092

0.322

0.349

0.436

Pre-miR-146a

5q34

rs2910164

G>C

99.81

0.468

0.429

0.558

0.558

Has-miR-605

10q21.1

rs2043556

A>G

99.77

0.753

0.281

0.004

0.020

Has-miR-608

10q25.1

rs4919510

G>C

99.85

0.835

0.425

0.245

0.408

Pre-miR-196a

12q13.13

rs11614913

A>G

99.91

0.796

0.432

0.019

0.048

  1. Italic value indicate significance of p value (p < 0.05)
  2. HWE Hardy–Weinberg equilibrium, MAF minor allele frequency
  3. aTwo-sided Chi squared test for the comparison of the allele frequency between HNSCC patients and cancer-free controls
  4. b P values adjusted by false discovery rate (FDR) method
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Cancer Communications

ISSN: 2523-3548

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