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Table 1 The relationship between miR-506 expression and clinicopathologic parameters in 110 PDACs

From: MicroRNA-506 is up-regulated in the development of pancreatic ductal adenocarcinoma and is associated with attenuated disease progression

Variable

No. of patients

miR-506 expression [case (%)]

χ2

P value

Low

High

Age (years)

 ≤59

57

41 (71.9)

16 (28.1)

2.194

0.139

 >59

53

31 (58.5)

22 (41.5)

  

Sex

 Men

63

45 (71.4)

18 (28.6)

2.327

0.127

 Women

47

27 (57.4)

20 (42.6)

  

Tumor site

 Head

51

35 (68.6)

16 (31.4)

1.551

0.461

 Uncinate process

32

22 (68.8)

10 (31.2)

  

 Body and tail

27

15 (55.6)

12 (44.4)

  

Tumor size (cm)

 ≤4

67

45 (67.2)

22 (32.8)

0.222

0.638

 >4

43

27 (62.8)

16 (37.2)

  

Histologic grade

 G1, G2

68

39 (57.4)

29 (42.6)

5.170

0.023

 G3

42

33 (78.6)

9 (21.4)

  

pT category

 T1, T2

28

12 (42.9)

16 (57.1)

8.482

0.004

 T3, T4

82

60 (73.2)

22 (26.8)

  

Lymph node metastasisa

 No

74

45 (60.8)

29 (39.2)

4.542

0.033

 Yes

21

18 (85.7)

3 (14.3)

  
  1. aNo information about lymph node metastasis in 15 patients