Preoperative neutrophil-to-lymphocyte ratio plus platelet-to-lymphocyte ratio in predicting survival for patients with stage I–II gastric cancer

Table 3 Univariate and multivariate Cox regression analyses of overall survival in 305 patients with stage I–II gastric cancer

Characteristic	Univariate analysis		Multivariate analysis
Characteristic	Hazard ratio (95% CI)	P	Hazard ratio (95% CI)	P
Age (<60 vs. ≥60 years)	2.43 (1.49–3.96)	<0.001	1.62 (0.91–2.89)	0.100
Sex (male vs. female)	0.61 (0.36–1.05)	0.075
Tumor location in the stomach (upper vs. middle vs. lower third)	0.59 (0.45–0.77)	<0.001	0.77 (0.56–1.07)	0.119
Tumor size (<3 vs. ≥3 cm)	1.26 (0.78–2.01)	0.344
TNM stage (IA vs. IB vs. IIA vs. IIB)	1.60 (1.25–2.05)	<0.001	1.36 (1.01–1.83)	0.041
mGPS (0 vs. 1 vs. 2)	1.86 (1.25–2.76)	0.002	1.24 (0.80–1.93)	0.345
PNI (0 vs. 1)	2.36 (1.21–4.62)	0.012	0.78 (0.31–1.93)	0.589
PLT–NLR (0 vs. 1 vs. 2)	1.40 (0.99–1.97)	0.057
NLR–PLR (0 vs. 1 vs. 2)	2.018 (1.50-2.72)	<0.001	1.51 (1.02–2.24)	0.039

mGPS modified glasgow prognostic score, PNI prognostic nutritional index, PLT platelet count, NLR neutrophil-to-lymphocyte ratio, PLR platelet-to-lymphocyte ratio

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