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Table 2 Univariate and multivariate Cox regression analyses of clinicopathologic variables of patients with early-stage cervical squamous cell cancer for overall survival

From: The expression and prognostic value of protein tyrosine kinase 6 in early-stage cervical squamous cell cancer

Variable Univariate analysis Multivariate analysis
HR 95% CI P value HR 95% CI P value
Age (>45 vs. ≤45 years) 2.906 0.911–9.268 0.071    
Tumor size (>4 vs. ≤4 cm) 0.608 0.239–1.545 0.295    
Tumor grade (1 + 2 vs. 3) 1.239 0.446–3.441 0.681    
SCC antigen level (>1.5 vs. ≤1.5 ng/mL) 1.477 0.512–4.264 0.471    
FIGO stage (IB1 + IB2 + IIA1 vs. IIB) 2.111 1.313–3.392 0.002 2.876 1.582–5.229 0.001
Pelvic lymph node metastasis (present vs. absent) 3.569 1.237–10.294 0.019 0.291 0.047–1.789 0.183
Deep cervical stromal invasion (present vs. absent) 5.385 1.205–24.065 0.028 1.548 0.266–8.999 0.626
Lymphovascular space invasion (present vs. absent) 13.212 4.575–38.156 <0.001 19.284 5.958–62.419 <0.001
PTK6 expression (high vs. low) 4.763 1.326–17.112 0.017 5.999 1.622–22.191 0.007
  1. HR hazard ratio, CI confidence interval, SCC squamous cell carcinoma