Table 1 Relationships between protein tyrosine kinase 6 (PTK6) expression level and clinicopathologic characteristics of the patients with early-stage squamous cervical cell cancer
Characteristic | Total (cases) | PTK6 expression [cases (%)] | χ2 value | P value | |
|---|---|---|---|---|---|
High | Low | ||||
Age (years) | 0.172 | 0.679 | |||
≤45 | 81 | 36 (44.4) | 45 (55.6) | ||
>45 | 69 | 33 (47.8) | 36 (52.2) | ||
Tumor size (cm) | 0.842 | 0.359 | |||
≤4 | 138 | 65 (47.1) | 73 (52.9) | ||
>4 | 12 | 4 (33.3) | 8 (66.7) | ||
Tumor grade | 7.651 | 0.020* | |||
1 | 6 | 6 (100) | 0 (0) | ||
2 | 38 | 18 (47.4) | 20 (52.6) | ||
3 | 106 | 45 (42.5) | 61 (57.5) | ||
Clinical stage | 3.484 | 0.323 | |||
IB1 | 99 | 45 (45.5) | 54 (54.5) | ||
IB2 | 12 | 4 (33.3) | 8 (66.7) | ||
IIA1 | 34 | 19 (55.9) | 15 (44.1) | ||
IIB | 5 | 1 (20.0) | 4 (80.0) | ||
Pelvic lymph node metastasis | 0.176 | 0.675 | |||
Absent | 109 | 49 (45.0) | 60 (55.0) | ||
Present | 41 | 20 (48.8) | 21 (51.2) | ||
Deep cervical stromal invasion | 2.028 | 0.154 | |||
Absent | 71 | 37 (52.1) | 34 (47.9) | ||
Present | 79 | 32 (40.5) | 47 (59.5) | ||
SCC antigen level (ng/mL) | 3.671 | 0.055 | |||
≤1.5 | 99 | 40 (40.4) | 59 (59.6) | ||
>1.5 | 51 | 29 (56.9) | 22 (43.1) | ||
Lymphovascular space invasion | 0.115 | 0.734 | |||
Absent | 134 | 61 (45.5) | 73 (54.5) | ||
Present | 16 | 8 (50.0) | 8 (50.0) | ||