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Fig. 4 | Chinese Journal of Cancer

Fig. 4

From: Attenuated LKB1-SIK1 signaling promotes epithelial-mesenchymal transition and radioresistance of non–small cell lung cancer cells

Fig. 4

Liver kinase B1 (LKB1)-salt-inducible kinase 1 (SIK1) signaling suppressed the epithelial–mesenchymal transition phenotype of A549R and H1299R cells. a Western blot analysis of LKB1, SIK1, and Zinc-finger E-box-binding homeobox factor 1 (ZEB1) expression in A549, A549R, H1299, and H1299R cells. b The quantification of the protein levels in a. *P < 0.05; **P < 0.01 (Student’s t test). c Western blot analysis of LKB1, SIK1, ZEB1, E-cadherin, and vimentin expression in A549R cells transfected with enhanced green fluorescent protein (EGFP) or EGFP-LKB1 (left panel), and H1299R cells transfected with shCtrl or shLKB1 (right panel). d The quantification of the protein levels in c. *P < 0.05; **P < 0.01 (Student’s t test)

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