Variable | No. of patients | HR (95% CI) | P value |
---|---|---|---|
Relapse | |||
 Therapy | |||
  Allo-HSCT | 45 | 1.00 |  |
  Chemotherapy only | 43 | 11.49 (4.43–29.82) | <0.001 |
 WT1 transcript levela | |||
  High | 48 | 1.00 |  |
  Low | 40 | 3.53 (1.64–7.62) | 0.001 |
 MRD test resultb | |||
  Negative | 53 | 1.00 |  |
  Positive | 35 | 2.30 (1.06–4.97) | 0.034 |
Treatment failure | |||
 Therapy | |||
  Allo-HSCT | 45 | 1.00 |  |
  Chemotherapy only | 43 | 5.85 (2.75–12.44) | <0.001 |
 WT1 transcript level | |||
  High | 48 | 1.00 |  |
  Low | 40 | 3.71 (1.82–7.56) | <0.001 |
 MRD test result | |||
  Negative | 53 | 1.00 |  |
  Positive | 35 | 2.33 (1.17–4.64) | 0.016 |
Mortality | |||
 Therapy | |||
  Allo-HSCT | 45 | 1.00 |  |
  Chemotherapy only | 43 | 4.34 (1.98–9.53) | <0.001 |
 WT1 transcript level | |||
  High | 48 | 1.00 |  |
  Low | 40 | 3.50 (1.56–7.82) | 0.002 |
 MRD test result | |||
  Negative | 53 | 1.00 |  |
  Positive | 35 | 2.32 (1.09–4.97) | 0.030 |