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Table 5 Clinical characteristics of 3893 patients with advanced NPC who were treated with different therapeutic modalities
From: A new prognostic histopathologic classification of nasopharyngeal carcinoma
| Characteristic | RT alone | RCT | P value |
|---|---|---|---|
| Total (cases) | 1077 | 2816 | |
| Age (years) | <0.001† | ||
| Median (range) | 48 (11–90) | 47 (10–85) | |
| Follow-up time (months) | <0.001† | ||
| Median (range) | 60 (2–120) | 52 (2–120) | |
| Sex [cases (%)] | 0.120* | ||
| Male | 785 (72.9) | 2120 (75.3) | |
| Female | 292 (27.1) | 696 (24.7) | |
| Clinical stage [cases (%)] | <0.001* | ||
| III | 685 (63.6) | 1144 (40.6) | |
| IV | 392 (36.4) | 1672 (59.4) | |
| Proposed classification [cases (%)] | <0.001* | ||
| EC | 622 (57.8) | 1845 (65.5) | |
| MSEC | 228 (21.2) | 531 (18.9) | |
| SC | 178 (16.5) | 320 (11.3) | |
| SCC | 49 (4.5) | 120 (4.3) | |
| WHO classification [cases (%)] | <0.001* | ||
| NKUC | 889 (82.5) | 2215 (78.6) | |
| NKDC | 160 (14.9) | 560 (20.0) | |
| KSCC | 28 (2.6) | 41 (1.4) | |
| OS rate (%) | <0.001§ | ||
| 5-year (95% CI) | 64.8 (61.7–67.6) | 75.6 (73.8–77.3) | |
