Table 3 Univariate analysis of the association between BPs and survival outcome
From: Association of perioperative blood pressure with long-term survival in rectal cancer patients
Variable | Blood pressure | No. of patients in low BP group/high BP group | DFS | CSS | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
Categorized, HR (95% CI) | Continuous HR (95% CI) | P | Categorized, HR (95% CI) | Continuous HR (95% CI) | P | |||||||
<Cut-off (ref) | ≥Cut-off | P | <Cut-off (ref) | ≥Cut-off | P | |||||||
Total | Preoperative BP | 358 | ||||||||||
SBP | 111/247 | 1.00 | 1.87 (1.11–3.17) | 0.019 | 1.01 (0.99–1.01) | 0.229 | 1.00 | 4.18 (1.48–11.83) | 0.007 | 1.00 (0.99–1.01) | 0.726 | |
DBP | 207/151 | 1.00 | 1.44 (0.93–2.23) | 0.107 | 1.01 (0.99–1.03) | 0.221 | 1.00 | 1.72 (0.89–3.31) | 0.106 | 1.00 (0.98–1.02) | 0.971 | |
Mid-BP | 161/197 | 1.00 | 1.54 (0.98–2.42) | 0.060 | 1.01 (0.99–1.03) | 0.121 | 1.00 | 1.73 (0.87–3.42) | 0.117 | 1.02 (0.99–1.04) | 0.145 | |
Postoperative BP | 358 | |||||||||||
SBP | 258/100 | 1.00 | 1.26 (0.79–1.98) | 0.330 | 1.00 (0.99–1.02) | 0.807 | 1.00 | 1.99 (1.05–3.78) | 0.035 | 1.01 (0.99–1.03) | 0.207 | |
DBP | 337/21 | 1.00 | 1.33 (0.61–2.88) | 0.477 | 1.01 (0.98–1.03) | 0.625 | 1.00 | 2.15 (0.84–5.53) | 0.111 | 1.03 (0.99–1.06) | 0.106 | |
Mid-BP | 306/52 | 1.00 | 1.63 (0.96–2.74) | 0.069 | 1.00 (0.99–1.02) | 0.716 | 1.00 | 2.34 (1.16–4.72) | 0.018 | 1.02 (0.99–1.05) | 0.131 | |
Sex | ||||||||||||
Men | Preoperative SBP | 62/135 | 1.00 | 1.89 (0.90–3.97) | 0.091 | 1.00 (0.99–1.01) | 0.701 | 1.00 | 3.37 (1.00–11.39) | 0.050 | 1.00 (0.99–1.01) | 0.777 |
Postoperative SBP | 145/59 | 1.00 | 1.35 (0.73–2.50) | 0.334 | 1.00 (0.98–1.02) | 0.957 | 1.00 | 1.76 (0.79–3.93) | 0.170 | 1.01 (0.98–1.03) | 0.450 | |
Women | Preoperative SBP | 45/108 | 1.00 | 1.79 (0.85–3.78) | 0.128 | 1.01 (0.99–1.02) | 0.230 | 1.00 | 6.16 (0.81–47.19) | 0.080 | 1.02 (0.99–1.04) | 0.191 |
Postoperative SBP | 113/41 | 1.00 | 1.25 (0.62–2.52) | 0.531 | 1.01 (0.99–1.03) | 0.509 | 1.00 | 2.32 (0.80–6.69) | 0.120 | 1.02 (0.98–1.05) | 0.380 | |
History of hypertension | ||||||||||||
Yes | Preoperative SBP | 5/61 | 1.00 | 1.13 (0.37–3.49) | 0.350 | 1.00 (0.99–1.02) | 0.665 | 1.00 | 0.85 (0.17–4.41) | 0.848 | 1.00 (0.98–1.02) | 0.959 |
Postoperative SBP | 25/41 | 1.00 | 0.56 (0.20–1.56) | 0.269 | 0.99 (0.96–1.03) | 0.746 | 1.00 | 0.40 (0.09–1.79) | 0.229 | 0.97 (0.92–1.02) | 0.180 | |
No | Preoperative SBP | 102/183 | 1.00 | 1.66 (0.96–2.85) | 0.070 | 1.00 (0.99–1.01) | 0.412 | 1.00 | 3.84 (1.34–11.05) | 0.012 | 1.00 (0.99–1.02) | 0.804 |
Postoperative SBP | 233/59 | 1.00 | 1.36 (0.80–2.31) | 0.255 | 0.99 (0.98–1.02) | 0.945 | 1.00 | 2.77 (1.36–5.66) | 0.005 | 1.02 (1.00–1.05) | 0.053 | |
BMI | ||||||||||||
BMI <23 | Preoperative SBP | 70/125 | 1.00 | 1.42 (0.75–2.69) | 0.283 | 1.00 (0.99–1.02) | 0.820 | 1.00 | 2.40 (0.79–7.24) | 0.120 | 0.99 (0.98–1.01) | 0.352 |
Postoperative SBP | 152/47 | 1.00 | 1.79 (0.96–3.33) | 0.066 | 1.01 (0.99–1.03) | 0.246 | 1.00 | 2.69 (1.13–6.38) | 0.025 | 1.02 (0.99–1.04) | 0.129 | |
BMI ≥23 | Preoperative SBP | 29/104 | 1.00 | 1.99 (0.69–5.70) | 0.201 | 1.00 (0.99–1.01) | 0.709 | 1.00 | 1.08 (0.23–5.00) | 0.247 | 1.01 (0.99–1.02) | 0.636 |
Postoperative SBP | 95/40 | 1.00 | 0.70 (0.31–1.58) | 0.394 | 0.98 (0.95–1.01) | 0.112 | 1.00 | 1.01 (0.30–3.36) | 0.987 | 0.99 (0.95–1.03) | 0.561 | |