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Table 3 Univariate analysis of the association between BPs and survival outcome

From: Association of perioperative blood pressure with long-term survival in rectal cancer patients

Variable Blood pressure No. of patients in low BP group/high BP group DFS CSS
Categorized, HR (95% CI) Continuous HR (95% CI) P Categorized, HR (95% CI) Continuous HR (95% CI) P
<Cut-off (ref) ≥Cut-off P <Cut-off (ref) ≥Cut-off P
Total Preoperative BP 358           
SBP 111/247 1.00 1.87 (1.11–3.17) 0.019 1.01 (0.99–1.01) 0.229 1.00 4.18 (1.48–11.83) 0.007 1.00 (0.99–1.01) 0.726
DBP 207/151 1.00 1.44 (0.93–2.23) 0.107 1.01 (0.99–1.03) 0.221 1.00 1.72 (0.89–3.31) 0.106 1.00 (0.98–1.02) 0.971
Mid-BP 161/197 1.00 1.54 (0.98–2.42) 0.060 1.01 (0.99–1.03) 0.121 1.00 1.73 (0.87–3.42) 0.117 1.02 (0.99–1.04) 0.145
Postoperative BP 358           
SBP 258/100 1.00 1.26 (0.79–1.98) 0.330 1.00 (0.99–1.02) 0.807 1.00 1.99 (1.05–3.78) 0.035 1.01 (0.99–1.03) 0.207
DBP 337/21 1.00 1.33 (0.61–2.88) 0.477 1.01 (0.98–1.03) 0.625 1.00 2.15 (0.84–5.53) 0.111 1.03 (0.99–1.06) 0.106
Mid-BP 306/52 1.00 1.63 (0.96–2.74) 0.069 1.00 (0.99–1.02) 0.716 1.00 2.34 (1.16–4.72) 0.018 1.02 (0.99–1.05) 0.131
Sex
 Men Preoperative SBP 62/135 1.00 1.89 (0.90–3.97) 0.091 1.00 (0.99–1.01) 0.701 1.00 3.37 (1.00–11.39) 0.050 1.00 (0.99–1.01) 0.777
Postoperative SBP 145/59 1.00 1.35 (0.73–2.50) 0.334 1.00 (0.98–1.02) 0.957 1.00 1.76 (0.79–3.93) 0.170 1.01 (0.98–1.03) 0.450
 Women Preoperative SBP 45/108 1.00 1.79 (0.85–3.78) 0.128 1.01 (0.99–1.02) 0.230 1.00 6.16 (0.81–47.19) 0.080 1.02 (0.99–1.04) 0.191
Postoperative SBP 113/41 1.00 1.25 (0.62–2.52) 0.531 1.01 (0.99–1.03) 0.509 1.00 2.32 (0.80–6.69) 0.120 1.02 (0.98–1.05) 0.380
History of hypertension
 Yes Preoperative SBP 5/61 1.00 1.13 (0.37–3.49) 0.350 1.00 (0.99–1.02) 0.665 1.00 0.85 (0.17–4.41) 0.848 1.00 (0.98–1.02) 0.959
Postoperative SBP 25/41 1.00 0.56 (0.20–1.56) 0.269 0.99 (0.96–1.03) 0.746 1.00 0.40 (0.09–1.79) 0.229 0.97 (0.92–1.02) 0.180
 No Preoperative SBP 102/183 1.00 1.66 (0.96–2.85) 0.070 1.00 (0.99–1.01) 0.412 1.00 3.84 (1.34–11.05) 0.012 1.00 (0.99–1.02) 0.804
Postoperative SBP 233/59 1.00 1.36 (0.80–2.31) 0.255 0.99 (0.98–1.02) 0.945 1.00 2.77 (1.36–5.66) 0.005 1.02 (1.00–1.05) 0.053
BMI
 BMI <23 Preoperative SBP 70/125 1.00 1.42 (0.75–2.69) 0.283 1.00 (0.99–1.02) 0.820 1.00 2.40 (0.79–7.24) 0.120 0.99 (0.98–1.01) 0.352
Postoperative SBP 152/47 1.00 1.79 (0.96–3.33) 0.066 1.01 (0.99–1.03) 0.246 1.00 2.69 (1.13–6.38) 0.025 1.02 (0.99–1.04) 0.129
 BMI ≥23 Preoperative SBP 29/104 1.00 1.99 (0.69–5.70) 0.201 1.00 (0.99–1.01) 0.709 1.00 1.08 (0.23–5.00) 0.247 1.01 (0.99–1.02) 0.636
Postoperative SBP 95/40 1.00 0.70 (0.31–1.58) 0.394 0.98 (0.95–1.01) 0.112 1.00 1.01 (0.30–3.36) 0.987 0.99 (0.95–1.03) 0.561
  1. DBP diastolic blood pressure, DFS disease-free survival, CSS cancer-specific survival, HR hazard ratio, CI confidence interval, SBP systolic blood pressure, BMI body mass index, BP blood pressure, AJCC American Joint Committee on Cancer, CEA carcinoembryonic antigen