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Table 1 Baseline characteristics and distribution of clinicopathologic variables for the 358 patients with rectal cancer

From: Association of perioperative blood pressure with long-term survival in rectal cancer patients

Variable Overall population Postoperative SBP (mmHg) P value
<120 ≥120
(n = 358) (n = 258) (n = 100)
Age (years)
 Median (range)a 60 (21–89) 58 (21–89) 65 (25–89) <0.001
 <60 174 (48.6) 143 (55.4) 31 (31.0) <0.001
 ≥60 184 (51.4) 115 (44.6) 69 (69.0)  
BMI (kg/m2)
 Median (range)a 22.1 (13.3–35.9) 22.0 (13.3–33.8) 22.7 (14.9–35.9) 0.080
 <23 199 (55.6) 152 (58.9) 47 (47.0) 0.219
 ≥23 135 (37.7) 95 (36.8) 40 (40.0)  
 Unknown 24 (6.7) 11 (4.3) 13 (13.0)  
Sex     0.631
 Men 204 (57.0) 145 (56.2) 59 (59.0)  
 Women 154 (43.0) 113 (43.8) 41 (41.0)  
History of hypertension     <0.001
 No 292 (81.6) 233 (90.3) 59 (59.0)  
 Yes 66 (18.4) 25 (9.7) 41 (41.0)  
History of smoking     0.001
 No 263 (73.5) 202 (78.3) 61 (61.0)  
 Yes 95 (26.5) 56 (21.7) 39 (39.0)  
Preoperative BP (mmHg)     
 Median (range)a 123 (73–201) 120 (73–184) 135 (97–201) <0.001
 <120 107 (29.9) 94 (36.4) 13 (13.0) <0.001
 120–140 171 (47.8) 130 (50.4) 41 (41.0)  
 ≥140 72 (20.1) 30 (11.6) 42 (42.0)  
 Unknown 8 (2.2) 4 (1.6) 4 (4.0)  
TNM stage, AJCC     0.537
 I 93 (26.0) 71 (27.5) 22 (22.0)  
 II 115 (32.1) 80 (31.0) 35 (35.0)  
 III 150 (41.9) 107 (41.5) 43 (43.0)  
Differentiation degree     0.353
 Low 68 (19.0) 47 (18.2) 21 (21.0)  
 Moderate 188 (52.5) 132 (51.2) 56 (56.0)  
 High 102 (28.5) 79 (30.6) 23 (23.0)  
Vascular invasion     0.782
 Negative 327 (91.3) 235 (91.1) 92 (92.0)  
 Positive 31 (8.7) 23 (8.9) 8 (8.0)  
Perineural invasion     0.698
 Negative 326 (91.1) 234 (90.7) 92 (92.0)  
 Positive 32 (8.9) 24 (9.3) 8 (8.0)  
Preoperative CEA     0.382
 Negative 252 (70.4) 185 (71.7) 67 (67.0)  
 Positive 106 (29.6) 73 (28.3) 33 (33.0)  
Distance from anal verge (cm)     0.831
 <5 132 (36.9) 96 (37.2) 36 (36.0)  
 5–12 226 (63.1) 162 (62.8) 64 (64.0)  
Intraoperative blood transfusion     0.514
 No 311 (86.9) 226 (87.6) 85 (85.0)  
 Yes 47 (13.1) 32 (12.4) 15 (15.0)  
Estimation of blood loss in operation [median (range); mL]a 100 (15–3000) 100 (20–3000) 100 (15–1000) 0.899
Adjuvant treatment     0.122
 No 177 (49.4) 121 (46.9) 56 (56.0)  
 Yes 181 (50.6) 137 (53.1) 44 (44.0)  
Neoadjuvant treatment     0.146
 No 315 (88.0) 223 (86.4) 92 (92.0)  
 Yes 43 (12.0) 35 (13.6) 8 (8.0)  
  1. SBP systolic blood pressure, BMI body mass index, BP blood pressure, AJCC American Joint Committee on Cancer, CEA carcinoembryonic antigen
  2. aThese values are presented as median followed by a range in the parentheses; other values are presented as the number of cases with a percentage in the following parentheses