Table 1 Baseline characteristics and distribution of clinicopathologic variables for the 358 patients with rectal cancer
From: Association of perioperative blood pressure with long-term survival in rectal cancer patients
Variable | Overall population | Postoperative SBP (mmHg) | P value | |
|---|---|---|---|---|
<120 | ≥120 | |||
(n = 358) | (n = 258) | (n = 100) | ||
Age (years) | ||||
Median (range)a | 60 (21–89) | 58 (21–89) | 65 (25–89) | <0.001 |
<60 | 174 (48.6) | 143 (55.4) | 31 (31.0) | <0.001 |
≥60 | 184 (51.4) | 115 (44.6) | 69 (69.0) | |
BMI (kg/m2) | ||||
Median (range)a | 22.1 (13.3–35.9) | 22.0 (13.3–33.8) | 22.7 (14.9–35.9) | 0.080 |
<23 | 199 (55.6) | 152 (58.9) | 47 (47.0) | 0.219 |
≥23 | 135 (37.7) | 95 (36.8) | 40 (40.0) | |
Unknown | 24 (6.7) | 11 (4.3) | 13 (13.0) | |
Sex | 0.631 | |||
Men | 204 (57.0) | 145 (56.2) | 59 (59.0) | |
Women | 154 (43.0) | 113 (43.8) | 41 (41.0) | |
History of hypertension | <0.001 | |||
No | 292 (81.6) | 233 (90.3) | 59 (59.0) | |
Yes | 66 (18.4) | 25 (9.7) | 41 (41.0) | |
History of smoking | 0.001 | |||
No | 263 (73.5) | 202 (78.3) | 61 (61.0) | |
Yes | 95 (26.5) | 56 (21.7) | 39 (39.0) | |
Preoperative BP (mmHg) | ||||
Median (range)a | 123 (73–201) | 120 (73–184) | 135 (97–201) | <0.001 |
<120 | 107 (29.9) | 94 (36.4) | 13 (13.0) | <0.001 |
120–140 | 171 (47.8) | 130 (50.4) | 41 (41.0) | |
≥140 | 72 (20.1) | 30 (11.6) | 42 (42.0) | |
Unknown | 8 (2.2) | 4 (1.6) | 4 (4.0) | |
TNM stage, AJCC | 0.537 | |||
I | 93 (26.0) | 71 (27.5) | 22 (22.0) | |
II | 115 (32.1) | 80 (31.0) | 35 (35.0) | |
III | 150 (41.9) | 107 (41.5) | 43 (43.0) | |
Differentiation degree | 0.353 | |||
Low | 68 (19.0) | 47 (18.2) | 21 (21.0) | |
Moderate | 188 (52.5) | 132 (51.2) | 56 (56.0) | |
High | 102 (28.5) | 79 (30.6) | 23 (23.0) | |
Vascular invasion | 0.782 | |||
Negative | 327 (91.3) | 235 (91.1) | 92 (92.0) | |
Positive | 31 (8.7) | 23 (8.9) | 8 (8.0) | |
Perineural invasion | 0.698 | |||
Negative | 326 (91.1) | 234 (90.7) | 92 (92.0) | |
Positive | 32 (8.9) | 24 (9.3) | 8 (8.0) | |
Preoperative CEA | 0.382 | |||
Negative | 252 (70.4) | 185 (71.7) | 67 (67.0) | |
Positive | 106 (29.6) | 73 (28.3) | 33 (33.0) | |
Distance from anal verge (cm) | 0.831 | |||
<5 | 132 (36.9) | 96 (37.2) | 36 (36.0) | |
5–12 | 226 (63.1) | 162 (62.8) | 64 (64.0) | |
Intraoperative blood transfusion | 0.514 | |||
No | 311 (86.9) | 226 (87.6) | 85 (85.0) | |
Yes | 47 (13.1) | 32 (12.4) | 15 (15.0) | |
Estimation of blood loss in operation [median (range); mL]a | 100 (15–3000) | 100 (20–3000) | 100 (15–1000) | 0.899 |
Adjuvant treatment | 0.122 | |||
No | 177 (49.4) | 121 (46.9) | 56 (56.0) | |
Yes | 181 (50.6) | 137 (53.1) | 44 (44.0) | |
Neoadjuvant treatment | 0.146 | |||
No | 315 (88.0) | 223 (86.4) | 92 (92.0) | |
Yes | 43 (12.0) | 35 (13.6) | 8 (8.0) | |