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Table 3 ALN metastasis state of 567 patients detected with SLNB and PLN sampling

From: Prospective study found that peripheral lymph node sampling reduced the false-negative rate of sentinel lymph node biopsy for breast cancer

SLN + PLN status ALN status Total
(+) (–)
(+) 183 (a′) 0 (c′) 183
(–) 8 (b′) 376 (d′) 384
Total 191 376 567
  1. For SLNB + PLN sampling, the FNR was \(\left( {{{\rm{b}}^\prime }} \right)/\left( {{{\rm{a}}^\prime }{\rm{ + }}{{\rm{b}}^\prime }} \right) = 8\;\left( {183{\rm{ + 8}}} \right) = 4.2\%\). Sensitivity was \(\left( {{{\rm{a}}^\prime }} \right)/\left( {{{\rm{a}}^\prime }{\rm{ + }}{{\rm{b}}^\prime }} \right) = 183\;\left( {183{\rm{ + 8}}} \right) = 95.8\%\). Accuracy rate was \({{\left( {{\text{a}}^{{\mathbf{\prime }}} {\mathbf{ + }}{\text{d}}^{{\mathbf{\prime }}} } \right)} \mathord{\left/ {\vphantom {{\left( {{\text{a}}^{{\mathbf{\prime }}} {\mathbf{ + }}{\text{d}}^{{\mathbf{\prime }}} } \right)} {\left( {{\text{a}}^{{\mathbf{\prime }}} \text{ + }{\text{b}}^{{\mathbf{\prime }}} {\mathbf{ + }}{\text{c}}^{{\mathbf{\prime }}} {\mathbf{ + }}{\text{d}}^{{\mathbf{\prime }}} } \right) = {{\left( {183\text{ + 376}} \right)} \mathord{\left/ {\vphantom {{\left( {183\text{ + 376}} \right)} {\left( {183{\mathbf{ + 8 + }}0{\mathbf{ + }}376} \right)}}} \right. \kern-0pt} {\left( {183{\mathbf{ + 8 + }}0{\mathbf{ + }}376} \right)}} = 98.6\% }}} \right. \kern-0pt} {\left( {{\text{a}}^{{\mathbf{\prime }}} \text{ + }{\text{b}}^{{\mathbf{\prime }}} {\mathbf{ + }}{\text{c}}^{{\mathbf{\prime }}} {\mathbf{ + }}{\text{d}}^{{\mathbf{\prime }}} } \right) = {{\left( {183\text{ + 376}} \right)} \mathord{\left/ {\vphantom {{\left( {183\text{ + 376}} \right)} {\left( {183{\mathbf{ + 8 + }}0{\mathbf{ + }}376} \right)}}} \right. \kern-0pt} {\left( {183{{ + 8 + }}0{\mathbf{ + }}376} \right)}} = 98.6\% }}\). Negative predictive value was \({{\left( {{\text{d}}^{{\mathbf{\prime }}} } \right)} \mathord{\left/ {\vphantom {{\left( {{\text{d}}^{{\mathbf{\prime }}} } \right)} {\left( {{\text{b}}^{{\mathbf{\prime }}} {\mathbf{ + }}{\text{d}}^{{\mathbf{\prime }}} } \right)}}} \right. \kern-0pt} {\left( {{\text{b}}^{{\mathbf{\prime }}} {\mathbf{ + }}{\text{d}}^{{\mathbf{\prime }}} } \right)}} = {{376} \mathord{\left/ {\vphantom {{376} {\left( {{{8 + }}376} \right)}}} \right. \kern-0pt} {\left( {{{8 + }}376} \right)}} = 97.9\%\)
  2. Abbreviations: ALN axillary lymph node, SLNB sentinel lymph node biopsy, PLN peripheral lymph node, SLN sentinel lymph node, FNR false-negative rate