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Table 2 Multivariate analysis of 215 patients with early-stage UADT-ENKTCL

From: Primary site and regional lymph node involvement are independent prognostic factors for early-stage extranodal nasal-type natural killer/T cell lymphoma

Variable Overall survival Progression-free survival
HR 95% CI P HR 95% CI P
Primary site (extra-nasal vs. nasal) 1.860 1.092–3.169 0.022 1.857 1.182–2.916 0.007
Regional lymph node involvement (yes vs. no) 1.796 1.080–2.986 0.024 1.716 1.116–2.637 0.014
Age (>60 vs. ≤60 years) 3.365 1.867–6.066 <0.001 1.720 0.984–3.006 0.057
Elevated LDH level (yes vs. no) 2.422 1.419–4.132 0.001 1.942 1.218–3.093 0.005
ECOG score (≥2 vs. 0–1) 2.439 1.410–5.690 0.040
  1. HR hazard ratio, CI confidence interval, UADT-ENKTCL upper aerodigestive tract-extranodal natural killer/T-cell lymphoma, LDH lactate dehydrogenase, LTI local tumor invasiveness, ECOG eastern cooperative oncology group