Primary site and regional lymph node involvement are independent prognostic factors for early-stage extranodal nasal-type natural killer/T cell lymphoma

Table 2 Multivariate analysis of 215 patients with early-stage UADT-ENKTCL

Variable	Overall survival			Progression-free survival
Variable	HR	95% CI	P	HR	95% CI	P
Primary site (extra-nasal vs. nasal)	1.860	1.092–3.169	0.022	1.857	1.182–2.916	0.007
Regional lymph node involvement (yes vs. no)	1.796	1.080–2.986	0.024	1.716	1.116–2.637	0.014
Age (>60 vs. ≤60 years)	3.365	1.867–6.066	<0.001	1.720	0.984–3.006	0.057
Elevated LDH level (yes vs. no)	2.422	1.419–4.132	0.001	1.942	1.218–3.093	0.005
ECOG score (≥2 vs. 0–1)	2.439	1.410–5.690	0.040	–	–	–

HR hazard ratio, CI confidence interval, UADT-ENKTCL upper aerodigestive tract-extranodal natural killer/T-cell lymphoma, LDH lactate dehydrogenase, LTI local tumor invasiveness, ECOG eastern cooperative oncology group

ISSN: 2523-3548