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Table 2 Patient selection criteria for accelerated partial breast irradiation (APBI)

From: Accelerated partial breast irradiation: advances and controversies

Organization Age (years) Tumor size (cm) Lymph node status LVSI Margin Multifocality DCIS Neoadjuvant therapy Histology
ASTRO [15]
 Suitable ≥60 ≤2 pN0 (i+/i) No Negative (≥2 mm) Clinically unifocal None None IDC
 Cautionary 50–59 2.1–3.0 Limited/focal Close (<2 mm) Clinically unifocal ≤3 cm ILC
 Unsuitable <50 >3 ≥pN1 Extensive Positive Multifocal >3 cm Used
ASBS [16] ≥45 ≤3 N0 Negative ≤3 cm IDC or DCIS
ABS [17] ≥50 ≤3 N0 Unifocal IDC
  1. LVSI lymphovascular space invasion, DCIS ductal carcinoma in situ, ASTRO American Society of Therapeutic Radiation Oncology, pNi pathologically positive node determined by immunohistochemistry with a size ≤ 0.2 mm, IDC invasive ductal carcinoma, ILC invasive lobular carcinoma, – not mentioned, ASBS American Society of Breast Surgeons, ABS American Brachytherapy Society