Variable | Subgroup 1 (n = 141) | Subgroup 2 (n = 51) | Subgroup 3 (n = 99) | Subgroup 4 (n = 154) | P 1 | P 2 | P 3 | P 4 |
---|---|---|---|---|---|---|---|---|
Age (years) | 0.290a | 0.042a | 0.108a | 0.526a | ||||
 Mean ± SDb | 48.4 ± 10.6 | 46.6 ± 9.6 | 50.7 ± 11.9 | 47.6 ± 11.7 | ||||
 <50 | 78 | 33 | 41 | 87 | ||||
 ≥50 | 63 | 18 | 58 | 67 | ||||
Gender | 0.216 | 0.527 | 0.988 | 0.092 | ||||
 Males | 124 | 48 | 87 | 131 | ||||
 Females | 17 | 3 | 12 | 23 | ||||
HBeAg | 0.011 | <0.001 | 0.441 | 0.360 | ||||
 Positive | 42 | 6 | 25 | 10 | ||||
 Negative | 99 | 45 | 74 | 144 | ||||
Tumor size (cm) | 0.233a | 0.922a | 0.158a | 0.020a | ||||
 Mean ± SDb | 4.8 ± 3.1 | 4.2 ± 2.8 | 5.4 ± 3.1 | 5.5 ± 3.3 | ||||
 <5 | 86 | 36 | 45 | 76 | ||||
 ≥5 | 55 | 15 | 54 | 78 | ||||
Tumor number | 0.460 | 0.194 | 0.278 | 0.360 | ||||
 Single | 131 | 45 | 88 | 144 | ||||
 Multiple | 10 | 6 | 11 | 10 | ||||
Pathologic grade | 0.561 | 0.375 | 0.498 | 0.444 | ||||
 I | 10 | 2 | 12 | 9 | ||||
 II | 85 | 36 | 56 | 94 | ||||
 III | 45 | 13 | 30 | 50 | ||||
 IV | 1 | 0 | 1 | 1 | ||||
Microvascular thrombus | 0.756 | 0.210 | 0.430 | 0.273 | ||||
 Yes | 19 | 6 | 10 | 9 | ||||
 No | 122 | 45 | 89 | 145 | ||||
Tumor capsule (cases) | 0.083 | 0.729 | 0.056 | 0.648 | ||||
 Complete | 64 | 23 | 43 | 69 | ||||
 Incomplete | 49 | 11 | 24 | 42 | ||||
 Without | 28 | 17 | 32 | 43 | ||||
Liver cirrhosis | 0.017 | 0.738 | 0.852 | 0.012 | ||||
 Yes | 101 | 45 | 72 | 109 | ||||
 No | 40 | 6 | 27 | 45 | ||||
AFP (ng/mL) | 0.216 | 0.514 | 0.897 | 0.523 | ||||
 ≤25 | 61 | 17 | 42 | 59 | ||||
 >25 | 80 | 34 | 57 | 95 | ||||
ALT (IU/L) | 0.052a | <0.001a | 0.485a | 0.220a | ||||
 Mean ± SDb | 52.4 ± 29.3 | 42.8 ± 32.1 | 49.8 ± 26.0 | 36.8 ± 22.3 | ||||
 ≤40 | 53 | 30 | 46 | 104 | ||||
 >40 | 88 | 21 | 53 | 50 | ||||
AST (IU/L) | 0.009a | 0.008a | 0.508a | 0.596a | ||||
 Mean ± SDb | 44.4 ± 27.1 | 33.7 ± 16.8 | 42.4 ± 17.6 | 35.5 ± 21.6 | ||||
 ≤45 | 96 | 42 | 62 | 127 | ||||
 >45 | 45 | 9 | 37 | 27 | ||||
ALB (g/L) | 0.028a | 0.092a | 0.372a | 0.168a | ||||
 Mean ± SDb | 42.8 ± 3.5 | 44.1 ± 3.7 | 42.3 ± 4.0 | 43.2 ± 3.9 | ||||
 <35 | 2 | 1 | 95 | 150 | ||||
 ≥35 | 139 | 50 | 4 | 4 | ||||
TBIL (μmol/L) | 0.931a | 0.878a | 0.114a | 0.193a | ||||
 Mean ± SDb | 16.0 ± 7.8 | 15.9 ± 5.8 | 14.5 ± 5.4 | 14.6 ± 5.8 | ||||
 ≤20.5 | 116 | 40 | 84 | 133 | ||||
 >20.5 | 25 | 11 | 15 | 21 | ||||
Prothrombin time (s) | 0.929a | 0.182a | 0.824a | 0.345a | ||||
 Mean ± SDb | 12.7 ± 1.5 | 12.7 ± 1.6 | 12.6 ± 1.3 | 12.4 ± 1.2 | ||||
 ≤13.5 | 101 | 38 | 76 | 131 | ||||
 >13.5 | 40 | 13 | 23 | 23 | ||||
Recurrence | 0.535 | 0.001 | 0.180 | 0.312 | ||||
 Yes | 79 | 26 | 64 | 66 | ||||
 No | 62 | 25 | 35 | 88 | ||||
Death | 0.189 | 0.001 | 0.731 | 0.276 | ||||
 Yes | 41 | 10 | 48 | 42 | ||||
 No | 100 | 41 | 51 | 112 |