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Table 4 Difference of co-existence of T790M mutation between patients with EGFR 19 del and L858R mutation

From: Clinical outcomes of EGFR-TKI treatment and genetic heterogeneity in lung adenocarcinoma patients with EGFR mutations on exons 19 and 21

Patient Exon 19 deletion Exon 21 L858R mutation P valuea
(n = 140) (n = 82)
T790M mutation pre-TKI 0.554
 Positive 3 (5.6) 3 (8.8)
 Negative 51 (94.4) 31 (91.2)  
T790M mutation post-TKI 0.176
 Positive 21 (24.4) 17 (35.4)
 Negative 65 (75.6) 31 (64.6)  
  1. aBy using χ2 test. All values are presented as the number of patients followed by the percentage in the parentheses