From: Why some tumours trigger neovascularisation and others don’t: the story thus far
Proteins equally expressed in angiogenic and non-angiogenictumours | Proteins up-regulated in angiogenic tumours | Proteins up-regulated in non-angiogenic tumours | |||
---|---|---|---|---|---|
Pathway | Databases | Pathway | Databases | Pathway | Databases |
Focal adhesion | KEGG, WikiPathways | Focal adhesion | KEGG, WikiPathways | – | – |
VEGF-related | KEGG, Panther, Reactome | – | – | – | – |
Angiogenesis | Panther, WikiPathways | Angiogenesis | Panther | Angiogenesis | Panther |
– | – | Itegrin signalling | Panther | – | – |
Oxidative stress | Panther, WikiPathways | – | – | – | – |
Cell response to stress | Reactome | – | – | – | – |
– | – | Delta-Notch | WikiPathways | – | – |
– | – | Collagen-related pathways | Reactome | – | – |
– | – | Cell–cell communication | Reactome | – | – |
– | – | Integrin signaling | Panther | – | – |
EGF-related pathways | WikiPathways, Panther | – | – | ||
– | – | – | – | Response to Hypoxia | Reactome |
Ephrins signaling | Reactome | – | – | Ephrins-related pathways | Reactome |
– | – | – | – | Regulation of HIF by oxygen | Reactome |
– | – | – | – | Regulation of genes by HIF | Reactome |
– | – | – | – | Nitrogen metabolism | KEGG |