Long-term outcomes of a phase II randomized controlled trial comparing intensity-modulated radiotherapy with or without weekly cisplatin for the treatment of locally recurrent nasopharyngeal carcinoma

Table 4 Morbidity events and causes for death

Item	CCRT group (34 patients)	RT group (35 patients)	χ²	P value^a
Item	n (%)	n (%)	χ²	P value^a
Morbidity and events
Nasopharyngeal massive hemorrhage	3 (8.8)	12 (34.3)	6.572	0.010
Nasopharyngeal mucosal necrosis	8 (23.5)	13 (37.1)	1.510	0.219
Radiation encephalopathy	4 (11.8)	5 (14.3)	0.097	0.756
Trismus	0 (0.0)	5 (14.3)	5.237	0.022
Anterior cranial nerve palsies	1 (2.9)	2 (5.7)	0.319	0.572
Posterior cranial nerve palsies	1 (2.9)	2 (5.7)	0.319	0.572
Causes for death
Recurrence	10 (29.4)	7 (20.0)	0.823	0.364
Distant metastasis	1 (2.9)	3 (8.6)	1.001	0.317
Rrecurrence + distant metastasis	2 (5.9)	2 (5.7)	0.001	0.976
Residual disease + progression	1 (2.9)	0 (0.0)	1.045	0.307
Other diseases	0 (0.0)	3 (8.6)	3.047	0.081
Nasopharyngeal hemorrhage	2 (5.9)	10 (28.6)	6.180	0.013
Radiation encephalopathy	4 (11.8)	2 (5.7)	0.795	0.373

ISSN: 2523-3548