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Table 2 Univariate analysis of overall survival (OS) for potential prognostic factors of patients with non-metastatic locally recurrent NPC

From: Long-term outcomes of a phase II randomized controlled trial comparing intensity-modulated radiotherapy with or without weekly cisplatin for the treatment of locally recurrent nasopharyngeal carcinoma

Variable Entire cohort (69 patients) χ2 P valuea CCRT group (34 patients) RT group (35 patients) χ2 P valuea
n 5-year OS rate (%) n 5-year OS rate (%) n 5-year OS rate (%)
Sex    0.810 0.368       
 Male 57 33.4    27 37.0 30 28.9 1.941 0.164
 Female 12 41.7    7 57.1 5 20.0 2.849 0.091
Age (years)    9.656 0.002       
 ≤46 38 46.3    22 43.0 16 50.0 0.039 0.843
 >46 31 19.9    12 38.5 19 10.5 3.385 0.066
rT categoryb    10.342 0.001       
 rT1–2 15 72.2    5 100 10 60.0 2.725 0.099
 rT3–4 54 24.2    29 33.0 25 13.2 6.789 0.009
rN categoryb    0.049 0.824       
 rN0 59 33.2    30 40.1 29 25.2 3.614 0.057
 rN1–2 10 44.4    4 50.0 6 40.0 0.161 0.688
Clinical stageb    8.613 0.003       
 I–II 16 67.7    6 83.3 10 60.0 1.042 0.307
 III–IV 53 24.7    28 34.3 25 13.2 7.574 0.006
Recurrence interval (months)    0.343 0.558       
 ≤30 39 36.0    21 37.5 18 33.3 0.126 0.723
 >30 30 33.4    13 49.0 17 20.6 5.664 0.017
Tumor volume (cm3)    9.352 0.002       
 ≤26 33 51.7    17 42.9 16 56.3 0.023 0.881
 >26 36 18.3    17 37.6 19 0.0 7.482 0.006
  1. Abbreviations as in Table 1
  2. aBy log-rank test
  3. bRestage according to the 2002 6th edition TNM staging system of the American Joint Commission on Cancer (AJCC)