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Table 1 Baseline characteristics of 69 patients with non-metastatic locally recurrent nasopharyngeal carcinoma (NPC)

From: Long-term outcomes of a phase II randomized controlled trial comparing intensity-modulated radiotherapy with or without weekly cisplatin for the treatment of locally recurrent nasopharyngeal carcinoma

Characteristic CCRT group RT group P valuea
(n = 34) (n = 35)
Sex (cases)    0.490
 Male 27 30  
 Female 7 5  
Age (years)    0.812
 Range 31–63 32–73  
 Median 42 48  
Interval of recurrence (months)    0.587
 Range 12–121 9–72  
 Median 26.5 30.0  
Initial radiation dose (Gy)    0.545
 Range 66–78 68–86  
 Median 70 72  
Pathology (cases)    0.532
 WHO type II 2 3  
 WHO type III 27 24  
 Diagnosed by clinical diagnosis (cases) 5 8  
 rT categoryb    0.175
  rT1 2 3  
  rT2 3 7  
  rT3 17 10  
  rT4 12 15  
 rN categoryb    0.778
  rN0 30 29  
  rN1 3 5  
  rN2 1 1  
Clinical stageb (cases)    0.448
 I 2 3  
 II 4 7  
 III 16 10  
 IV 12 15  
Pre-treatment serious complicationsc (cases)    0.618
 No 26 27  
 Yes 8 8  
Tumor volume (cm3)    0.242
 Range 3–146 7–116  
 Median 28 29  
Initial treatment modality (cases)    0.543
 Radiochemotherapy 11 9  
 Radiotherapy alone 23 26  
Initial irradiation technique (cases)    0.218
 2D 34 32  
 3D-CRT 0 2  
 IMRT 0 1  
  1. WHO World Health Organization, 2D two-dimension conventional radiotherapy, 3D-CRT three-dimension conformal radiotherapy, IMRT intensity-modulated radiotherapy, CCRT concomitant chemoradiotherapy, RT radiotherapy alone
  2. aBy χ2 test
  3. bRestage according to the 2002 6th edition TNM staging system of the American Joint Commission on Cancer (AJCC)
  4. cPre-treatment serious complications include trismus, radiation encephalopathy, and posterior cranial nerve palsies