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Table 5 The frequencies of RPMS1 SNP G155391A in NPC cases and healthy controls from various world regions

From: A single nucleotide polymorphism in the Epstein-Barr virus genome is strongly associated with a high risk of nasopharyngeal carcinoma

Sample Source Region No. (sum) G155391A Frequency of G155391A (%) NPC incidence P*
G G/A A
NPC TB Shandong 36 23 0 13 36.1 Low  
   Guangdong 122 22 0 100 82.0 High  
   Hong Kong 30 2 0 28 93.3 High  
   Singapore 30 9 0 21 70.0 High <0.001
  TW Shandong 22 17 0 5 22.7 Low  
   Guangdong 1051 155 24 872 83.0 High <0.001
Healthy subjects TW Europe 11 11 0 0 0.0 Low  
   Henan 83 81 1 1 1.2 Low  
   Beijing 100 91 1 8 8.0 Low  
   Shanxi 116 109 1 6 5.2 Low  
   Shandong 612 560 18 34 5.6 Low  
   Guangdong 1440 614 129 697 48.4 High <0.001
  1. TB tumor biopsy. Other abbreviations as in Tables 1 and 2
  2. * Data combined in regions with low/high NPC incidence and probability calculated by Fisher’s exact test