Table 4 Relationship between tumor location and clinicopathologic factors of NSCLC patients
Characteristic | Node-negative patients (pN0) | Node-positive patients (pN1–2) | ||||
|---|---|---|---|---|---|---|
LLL (n = 66) | Non-LLL (n = 324) | P | LLL (n = 41) | Non-LLL (n = 196) | P | |
Sex | 0.702 | 0.264 | ||||
Men | 47 (71.2) | 223 (68.8) | 25 (61.0) | 137 (69.9) | ||
Women | 19 (28.8) | 101 (31.2) | 16 (39.0) | 59 (30.1) | ||
Age | 0.341 | 0.463 | ||||
≤60 years | 31 (47.0) | 173 (53.4) | 27 (65.9) | 117 (59.7) | ||
>60 years | 35 (53.0) | 151 (46.6) | 14 (34.1) | 79 (40.3) | ||
T category | 0.291 | 1.000b | ||||
T1 | 9 (13.6) | 59 (18.2) | 4 (9.8) | 18 (9.2) | ||
T2 | 45 (68.2) | 227 (70.1) | 33 (80.5) | 157 (80.1) | ||
T3 | 12 (18.2) | 38 (11.7) | 4 (9.8) | 21 (10.7) | ||
N category | NA | 0.170 | ||||
N1 | 0 | 0 | 15 (36.6) | 51 (26.0) | ||
N2 | 0 | 0 | 26 (63.4) | 145 (74.0) | ||
TNM stage | 0.445c | 0.081d | ||||
Ia/b | 63 (95.5) | 299 (92.3) | 0 | 0 | ||
IIa/b | 3 (4.5) | 25 (7.7) | 15 (36.6) | 46 (23.5) | ||
IIIa | 0 | 0 | 26 (63.4) | 150 (76.5) | ||
Histology | 0.260 | 1.000b | ||||
AC | 30 (45.5) | 183 (56.5) | 26 (63.4) | 124 (63.3) | ||
SCC | 27 (40.9) | 105 (32.4) | 10 (24.4) | 49 (25.0) | ||
Others | 9 (13.6) | 36 (11.1) | 5 (12.2) | 23 (11.7) | ||
Histology grade | 0.023 | 0.256b | ||||
G1 | 14 (21.2) | 68 (21.0) | 2 (4.9) | 19 (9.7) | ||
G2 | 13 (19.7) | 117 (36.1) | 10 (24.4) | 66 (33.7) | ||
G3 | 39 (59.1) | 139 (42.9) | 29 (70.7) | 111 (56.6) | ||
Tumor size | <0.001 | 0.801 | ||||
≤4 cm | 29 (43.9) | 230 (71.0) | 27 (65.9) | 125 (63.8) | ||
>4 cm | 37 (56.1) | 94 (29.0) | 14 (34.1) | 71 (36.2) | ||
Pleural invasion | 0.343 | 1.000b | ||||
Yes | 57 (86.4) | 264 (81.5) | 37 (90.2) | 178 (90.8) | ||
No | 9 (13.6) | 60 (18.5) | 4 (9.8) | 18 (9.2) | ||
Adjuvant chemotherapy | 0.063 | 0.050 | ||||
Yes | 9 (13.6) | 78 (24.1) | 30 (73.2) | 111 (56.6) | ||
No | 57 (86.4) | 246 (75.9) | 11 (26.8) | 85 (43.4) | ||
No. of MLNs dissecteda | 4 (3, 17) | 7.5 (3, 44) | <0.001 | 5 (3, 14) | 8 (3, 38) | <0.001 |