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Table 1 Preoperative DA score and clinicopathologic variables in 260 patients with ESCC

From: Cumulative scores based on plasma D-dimer and serum albumin levels predict survival in esophageal squamous cell carcinoma patients treated with transthoracic esophagectomy

Characteristic No. of patients Score 0 (n = 55) Score 1 (n = 116) Score 2 (n = 89) P value
Sex      0.414
 Female 43 6 (14.0) 22 (51.2) 15 (34.9)  
 Male 217 49 (22.6) 94 (43.3) 74 (34.1)  
Age (years)      <0.001
 ≤59 138 43 (31.2) 61 (44.2) 34 (24.6)  
 >59 122 12 (9.8) 55 (45.1) 55 (45.1)  
Tumor location      0.387
 Upper-thoracic esophagus 21 4 (19.0) 10 (47.6) 7 (33.3)  
 Middle-thoracic esophagus 165 36 (21.8) 79 (47.9) 50 (30.3)  
 Lower-thoracic esophagus 74 15 (20.3) 27 (36.5) 33 (43.2)  
Tumor size (cm)      0.079
 <4 126 27 (21.4) 64 (50.8) 35 (27.8)  
 ≥4 134 28 (20.9) 52 (38.8) 54 (40.3)  
Pathologic grade      0.383
 I/II 179 36 (20.1) 85 (47.5) 58 (32.4)  
 III 81 19 (23.5) 31 (38.3) 31 (38.3)  
TNM stage      0.390
 I–IIA 102 22 (21.6) 50 (49.0) 30 (29.4)  
 IIB–IV 158 33 (20.9) 66 (41.8) 59 (37.3)  
T category      0.373
 1 + 2 50 13 (26.0) 18 (36.0) 19 (38.0)  
 3 + 4 210 42 (20.0) 98 (46.7) 70 (33.3)  
N category      0.695
 0 107 22 (20.6) 51 (47.7) 34 (31.8)  
 1 153 33 (21.6) 65 (42.5) 55 (35.9)  
HBsAg      0.052
 Negative 238 46 (19.3) 109 (45.8) 83 (34.9)  
 Positive 19 8 (42.1) 5 (26.3) 6 (31.6)  
Family historya      0.032
 No 236 45 (19.1) 109 (46.2) 82 (34.7)  
 Yes 24 10 (41.7) 7 (29.2) 7 (29.2)  
  1. All values are presented as numbers of patients followed by percentages in parentheses
  2. DA score D-dimer and albumin score, ESCC esophageal squamous cell carcinoma
  3. aPatients whose first-grade relatives have a history of esophageal cancer