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Fig. 2 | Chinese Journal of Cancer

Fig. 2

From: Differentiation therapy: a promising strategy for cancer treatment

Fig. 2

Restoring IkB kinase α (IKKα) promotes nasopharyngeal carcinoma differentiation. In undifferentiated NPC cells, IKKα is epigenetically suppressed by enhancer of zeste homologue 2 (EZH2) (left). After ATRA treatment, IKKα is restored, and the tumor cells differentiate towards normal cells (right). EED, embryonic ectoderm development; SUZ12, suppressor of zeste 12

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