Skip to main content

Advertisement

Table 2 Domain distribution of cancer-related MxA single-point mutations

From: Structural analysis of tumor-related single amino acid mutations in human MxA protein

MxA segment Mutation(s) in cancers
GTPase domain (G domain) L95P, P96S, S134L, P218S, V263M, R310S, K326N
Bundle-signaling-element domain (BSE) L643V, R649W, T651M, R654Q, R655C
Stalk G392V, V449G, N491K, R522C, L619I
Hinge 1 E632K
L4 G540D, Y538C, S572Y
N′-loop T27S