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Table 2 Domain distribution of cancer-related MxA single-point mutations

From: Structural analysis of tumor-related single amino acid mutations in human MxA protein

MxA segment

Mutation(s) in cancers

GTPase domain (G domain)

L95P, P96S, S134L, P218S, V263M, R310S, K326N

Bundle-signaling-element domain (BSE)

L643V, R649W, T651M, R654Q, R655C

Stalk

G392V, V449G, N491K, R522C, L619I

Hinge 1

E632K

L4

G540D, Y538C, S572Y

N′-loop

T27S