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Table 1 Summary of reported human myxovirus resistant protein A (MxA) single-point mutations in human cancers

From: Structural analysis of tumor-related single amino acid mutations in human MxA protein

Cancer type

Mutation(s)

Colorectal cancer

S134L, N491K, R522C, T651M, R654Q, V263M, Y538C, S572Y, R655C (2)a

Head and neck squamous cell carcinoma

T651M

Follicular lymphoma

T27S

Cutaneous squamous cell carcinoma

L95P, P96S, P218S

Mantle cell lymphoma

G540D, L643V

Embryonal rhabdomyosarcoma

V449G

Renal cell carcinoma

G392V

Prostate cancer

K326N

Lung adenocarcinoma

R310S

Melanoma

E632K

Medulloblastoma

R649W

Ovarian carcinoma

L619I

  1. aR655C mutation was discovered in colorectal cancer in two individual sequencing projects