Table 2 Univariate survival analysis of 194 HNSCC patients
Variable | OS | DFS | ||
|---|---|---|---|---|
RR (95% CI) | P value | RR (95% CI) | P value | |
Male | 1.49 (0.84–2.65) | 0.173 | 1.28 (0.81–2.04) | 0.295 |
Chronic illness | 1.23 (0.72–2.10) | 0.445 | 0.95 (0.59–1.52) | 0.819 |
Tobacco use | 1.59 (0.99–2.55) | 0.051 | 1.44 (0.97–2.14) | 0.067 |
Alcohol use | 1.95 (1.23–3.09) | 0.004 | 1.46 (0.98–2.18) | 0.065 |
Age >70 years | 1.18 (0.51–2.71) | 0.698 | 1.00 (0.49–2.05) | 0.991 |
Age <45 years | 1.08 (0.65–1.81) | 0.771 | 1.04 (0.67–1.59) | 0.876 |
Poor tumor differentiation | 2.02 (1.30–3.13) | 0.001 | 1.96 (1.35–2.83) | <0.001 |
Without neck dissection | 0.79 (0.47–1.31) | 0.357 | 1.54 (1.04–2.27) | 0.029 |
Tiam1 overexpression | 3.67 (2.12–6.34) | <0.001 | 2.05 (1.38–3.05) | <0.001 |
Stage III/IV disease | 3.39 (2.16–5.31) | <0.001 | 2.36 (1.63–3.42) | <0.001 |
Oral cavity cancer | 1.13 (0.68–1.90) | 0.630 | 2.48 (1.68–3.67) | <0.001 |
Adjuvant radiotherapy | 0.64 (0.38–1.08) | 0.091 | 0.86 (0.54–1.37) | 0.515 |