Tissue type | Cell line(s) | Potential inhibitor(s) of Wnt3a | Reference(s) |
---|---|---|---|
Breast cancer | EpRas MDA-MB-231, T-47D MDA-MB-231 MCF-7 | Knockdown of MARCKS-related protein Niclosamide and silibinin Kallistatin Deep-sea water β-estradiol Knockdown of FAK protein | [88] [99] [114] [49] [95] |
Colon cancer | SW480 | MEK inhibitor PD98059, genistein, and wortmannin | [100] |
Gastric cancer | Gastric cancer cells | Receptor for activated protein kinase C | [103] |
Leukemia | U937 | Cordycepin | [107] |
Liver cancer | Huh-7 | Variant 3 of collagen XVIII HS20 | [89] [96] |
Multiple myeloma | OPM-2, and MM patients’ plasma cells | DKK1 | [92] |
Melanoma | A375 and A2058 | Loss of FAM129B | [94] |
Prostate cancer | C4-2B PC-3 and DU145 | Axin Niclosamide and silibinin | [79] |
Renal carcinoma | ACHN | Enhancer of zeste homolog 2 small interfering RNA | [93] |
Teratocarcinoma | F9 NT2 | RGS19 All-trans-retinoic acid | [104] [115] |
HEK293 | HEK293 | Etinoic acid Variant 3 of collagen XVIII Purified recombinant frizzled cysteine-rich domain MEK inhibitor PD98059, genistein, and wortmannin Aspirin and norcantharidin Hexachlorophene Demethoxycurcumin and bisdemethoxycurcumin Mesd C-terminal region peptide and full-length Mesd protein A diterpenoid derivative, 15-oxospiramilactone Niclosamide and silibinin Magnolo l | [49] [89] [98] [100] [108] [109] [110] [105] [106] [116] |
Embryos | Cytotrophoblasts Neural plate | DKK1 Knockdown of FAK | [15] [95] |
B lymphopoiesis | CD133+CD10−CD10+ cells | DKK1 | [30] |
Fibroblasts | NIH3T3 | Chondroitin sulfate-E | [97] |
Osteoblasts Osteoblast-like cells | Osteoblasts Saos-2, MG63, C2C12, and hFOB1.19 C2C12 | DKK1 DKK1 Mesd C-terminal region peptide | [90] [105] |