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Table 3 Clinicopathologic parameters and expression of IGFBP-3 for the prognosis of 70 ESCC patients by univariate survival analysis (log-rank test)

From: Association of insulin-like growth factor-binding protein-3 with radiotherapy response and prognosis of esophageal squamous cell carcinoma

Variable All cases Mean survival (months) Median survival (months) P valuea
Ageb 0.739
 >60 years 57 29.2 13.0
 ≤60 years 13 19.0 18.0
Sex 0.036
 Male 45 19.4 13.0
 Female 25 46.4 24.0
Location 0.316
 Cervical 9 31.9 19.0
 Thoracic 61 26.8 13.0
Tumor sizec 0.028
 >6 cm 22 14.3 13.0
 ≤6 cm 48 33.7 20.0
WHO grade 0.721
 G1 9 28.4 19.0
 G2 29 28.0 12.0
 G3–4 32 24.0 18.0
T category <0.001
 T1–3 50 37.0 17.0
 T4 20 16.7 12.0
N category 0.003
 N0 21 32.4 18.0
 N1 49 23.4 14.0
M category 0.006
 M0 50 33.9 19.0
 M1-lymd 20 15.1 12.0
Clinical stage
 II 19 41.8 25.0 0.067
 III 31 25.3 13.0
 IV 20 15.1 12.0
IGFBP-3 expression <0.001
 High 32 44.6 25.0
 Low 38 10.9 10.0
  1. WHO World Health Organization
  2. aBy χ2 test
  3. bMean age
  4. cMean tumor size
  5. dDistant lymph node metastasis