Table 3 Clinicopathologic parameters and expression of IGFBP-3 for the prognosis of 70 ESCC patients by univariate survival analysis (log-rank test)
Variable | All cases | Mean survival (months) | Median survival (months) | P valuea |
|---|---|---|---|---|
Ageb | 0.739 | |||
>60 years | 57 | 29.2 | 13.0 | |
≤60 years | 13 | 19.0 | 18.0 | |
Sex | 0.036 | |||
Male | 45 | 19.4 | 13.0 | |
Female | 25 | 46.4 | 24.0 | |
Location | 0.316 | |||
Cervical | 9 | 31.9 | 19.0 | |
Thoracic | 61 | 26.8 | 13.0 | |
Tumor sizec | 0.028 | |||
>6 cm | 22 | 14.3 | 13.0 | |
≤6 cm | 48 | 33.7 | 20.0 | |
WHO grade | 0.721 | |||
G1 | 9 | 28.4 | 19.0 | |
G2 | 29 | 28.0 | 12.0 | |
G3–4 | 32 | 24.0 | 18.0 | |
T category | <0.001 | |||
T1–3 | 50 | 37.0 | 17.0 | |
T4 | 20 | 16.7 | 12.0 | |
N category | 0.003 | |||
N0 | 21 | 32.4 | 18.0 | |
N1 | 49 | 23.4 | 14.0 | |
M category | 0.006 | |||
M0 | 50 | 33.9 | 19.0 | |
M1-lymd | 20 | 15.1 | 12.0 | |
Clinical stage | ||||
II | 19 | 41.8 | 25.0 | 0.067 |
III | 31 | 25.3 | 13.0 | |
IV | 20 | 15.1 | 12.0 | |
IGFBP-3 expression | <0.001 | |||
High | 32 | 44.6 | 25.0 | |
Low | 38 | 10.9 | 10.0 | |