Fig. 1

Receiver operating characteristic (ROC) analysis was performed to determine the cut-off score for the positive expression of insulin-like growth factor-binding protein-3 (IGFBP-3) in 70 esophageal squamous cell carcinoma (ESCC) patients. The sensitivity and specificity for each outcome were plotted: a T category, b N category, c M category, d tumor grade, e survival status, and f progression-free survival