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Table 3 Toxicities after mobilization in 39 patients with high-risk non-Hodgkin’s lymphoma

From: Autologous peripheral blood stem cell mobilization following dose-adjusted cyclophosphamide, doxorubicin, vincristine, and prednisolone chemotherapy alone or in combination with rituximab in treating high-risk non-Hodgkin’s lymphoma

Parameter R-CHOP (n = 14) CHOP (n = 25) P value
Time from mobilization to the nadir of WBC (days)a 12 (9–14) 11 (0–16) 0.104
WBC count at nadir (×109/L)a 1.24 (0.23–2.60) 1.30 (0.06–3.70) 0.856
Time from mobilization to the nadir of neutrophils (days)a 12.5 (9–15) 11 (5–15) 0.042
Neutrophil count at nadir (×109/L)a 0.46 (0–1.60) 0.50 (0–2.41) 0.915
Time from mobilization to the nadir of PLT (days)a 14.5 (11–19) 13.0 (6–16) 0.008
PLT count at nadir (×109/L)a 97.5 (51–171) 97.0 (12–193) 0.797
PLT transfusions [cases (%)] 1 (7.1) 2 (8.0) 0.748
Vomiting [cases (%)]    0.805
 Grade 1/2 8 (57.1) 18 (72.0)  
 Grade 3 1 (7.1) 2 (8.0)  
Febrile neutropenia [cases (%)] 3 (21.4) 9 (36.0) 0.477
Diarrhea [cases (%)] 0 4 (16.0) 0.387
ALT elevation [cases (%)] 5 (35.7) 15 (60.0) 0.234
Anemia [cases (%)]    0.212
 Grade 1/2 7 (50.0) 20 (80.0)  
 Grade 3 1 (7.1) 1 (4.0)  
  1. PLT platelets, ALT alanine transaminase. Other abbreviations as in Tables 1 and 2
  2. aThe values are presented as median followed by range in parentheses; other values are presented as the number of patients followed by percentages in parentheses