Skip to main content

Table 2 Genes up-regulated or down-regulated at least 1.5-fold by overexpression of CYB5R2 in HONE1 cells

From: Cytochrome b5 reductase 2 suppresses tumor formation in nasopharyngeal carcinoma by attenuating angiogenesis

Pathway Gene symbol Name of gene Fold change in expression
Apoptosis and cell senescence FAS Fas (tumor necrosis factor receptor superfamily member 6) 1.81
Signal transduction and transcription FOS FBJ murine osteosarcoma viral oncogene homolog 1.86
PIK3R1 Phosphoinositide-3-kinase regulatory subunit 1 (alpha) 1.57
Adhesion ITGB3 Integrin beta 3 (platelet glycoprotein IIIa, antigen CD61) 1.68
MTSS1 Metastasis suppressor 1 1.59
ITGB5 Integrin beta 5 −8.72
Angiogenesis IFNB1 Interferon beta 1, fibroblast 1.84
VEGFA Vascular endothelial growth factor A −1.69
IGF1 Insulin-like growth factor 1 (somatomedin C) −1.57
TEK TEK tyrosine kinase, endothelial −10.28
TGFBR1 Transforming growth factor beta receptor 1 −1.71
Cell cycle control and DNA damage repair CDKN2A Cyclin-dependent kinase inhibitor 2A 1.57