CYB5R2 inhibits angiogenesis in NPC cell xenografts in a chick chorioallantoic membrane (CAM) model. a Representative images of xenograft tumors and surrounding blood vessels at 5 days after implantation with CNE2 or HONE1 cells that were transfected with CYB5R2 expression plasmid or empty vector plasmid. b Tumor volume measured on images of a. c Blood vessel area measured on images of a. d Relative expression of CYB5R2 in tumors from CAM models at 5 days after implantation. Data are presented as mean ± SD of three experiments. *P < 0.05.