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Table 4 Associations of CRP-SAA, total SAA, and CRP with survival of lung cancer patients in both the retrospective cohort and the prospective cohort

From: The prognostic value of serum C-reactive protein-bound serum amyloid A in early-stage lung cancer

Variate The retrospective cohort The prospective cohort
Stages I–IV Stages I–II Stages III–IV Stages I–IV Stages I–II Stages III–IV
CRP-SAA
 High level 33.1 21.48
 Low level 14.9 14.15
 HR 2.181 1.999 1.808 2.744 2.613 2.209
 95% CI 1.641–2.897 1.070–3.737 1.307–2.500 1.810–4.161 1.211–5.635 1.336–3.652
 P value <0.001 0.026 <0.001 <0.001 0.01 0.001
Total SAA
 High level 30.25 21.04
 Low level 16.46 14.6
 HR 1.697 1.27 1.631 1.775 0.44 1.602
 95% CI 1.281–2.248 0.692–2.331 1.180–2.255 1.243–2.533 0.105–1.851 1.079–2.378
 P value <0.001 0.436 0.002 0.001 0.246 0.016
CRP
 High level 30.59 21.35
 Low level 15.68 14.15
 HR 2.03 1.565 1.794 2.185 1.64 1.874
 95% CI 1.529–2.696 0.828–2.959 1.299–2.477 1.534–3.112 0.774–3.474 1.238–2.836
 P value <0.001 0.162 <0.001 0.001 0.189 0.002
  1. Abbreviations as in previous Tables. “–” indicates that the cumulative survival rate is below 50%. For grouping, the cutoff OD value for CRP-SAA is 0.10; the cutoff OD value for total SAA is 0.17; and the cutoff value of CRP is 8 mg/L.