Table 4 Associations of CRP-SAA, total SAA, and CRP with survival of lung cancer patients in both the retrospective cohort and the prospective cohort
From: The prognostic value of serum C-reactive protein-bound serum amyloid A in early-stage lung cancer
Variate | The retrospective cohort | The prospective cohort | ||||
|---|---|---|---|---|---|---|
Stages I–IV | Stages I–II | Stages III–IV | Stages I–IV | Stages I–II | Stages III–IV | |
CRP-SAA | ||||||
High level | 33.1 | – | 21.48 | – | – | – |
Low level | 14.9 | – | 14.15 | – | – | – |
HR | 2.181 | 1.999 | 1.808 | 2.744 | 2.613 | 2.209 |
95% CI | 1.641–2.897 | 1.070–3.737 | 1.307–2.500 | 1.810–4.161 | 1.211–5.635 | 1.336–3.652 |
P value | <0.001 | 0.026 | <0.001 | <0.001 | 0.01 | 0.001 |
Total SAA | ||||||
High level | 30.25 | – | 21.04 | – | – | – |
Low level | 16.46 | – | 14.6 | – | – | – |
HR | 1.697 | 1.27 | 1.631 | 1.775 | 0.44 | 1.602 |
95% CI | 1.281–2.248 | 0.692–2.331 | 1.180–2.255 | 1.243–2.533 | 0.105–1.851 | 1.079–2.378 |
P value | <0.001 | 0.436 | 0.002 | 0.001 | 0.246 | 0.016 |
CRP | ||||||
High level | 30.59 | – | 21.35 | – | – | – |
Low level | 15.68 | – | 14.15 | – | – | – |
HR | 2.03 | 1.565 | 1.794 | 2.185 | 1.64 | 1.874 |
95% CI | 1.529–2.696 | 0.828–2.959 | 1.299–2.477 | 1.534–3.112 | 0.774–3.474 | 1.238–2.836 |
P value | <0.001 | 0.162 | <0.001 | 0.001 | 0.189 | 0.002 |