Characteristic | Number of patients (%) | ALK rearrangement [cases (%)] | P | |
---|---|---|---|---|
Negative | Positive | |||
Total | 487 | 443 (91.0) | 44 (9.0) | Â |
Age | ||||
 ≤58 years | 261 (53.6) | 229 (51.7) | 32 (72.7) | 0.008 |
 >58 years | 226 (46.4) | 214 (48.3) | 12 (27.3) |  |
Sex | ||||
 Male | 303 (62.2) | 279 (63.0) | 24 (54.5) | 0.271 |
 Female | 184 (37.8) | 164 (37.0) | 20 (45.5) |  |
Histological type | ||||
 Adenocarcinoma | 382 (78.4) | 339 (76.5) | 43 (97.7) | 0.001 |
 Others | 105 (21.6) | 104 (23.5) | 1 (2.3) |  |
Differentiation | ||||
 Well | 206 (42.3) | 187 (42.2) | 19 (43.2) | 0.901 |
 Poor | 281 (57.7) | 256 (57.8) | 25 (56.8) |  |
Clinical stage | ||||
 I + II | 226 (46.4) | 213 (48.1) | 13 (29.5) | 0.019 |
 III + IV | 261 (53.6) | 230 (51.9) | 31 (70.5) |  |
Smoking history | ||||
 Non-smoker | 239 (49.1) | 207 (46.7) | 32 (72.7) | 0.001 |
 Smoker | 248 (50.9) | 236 (53.3) | 12 (27.3) |  |
EGFR mutation status | Â | Â | Â | Â |
 Negative | 328 (67.4) | 285 (64.3) | 43 (97.7) | <0.001 |
 Positive | 159 (32.6) | 158 (35.7) | 1 (2.3) |  |