Table 1 Baseline characteristics of 505 nasopharyngeal carcinoma (NPC) patients with synchronous metastasis
Characteristic | Entire group | M1 subcategorya | P value | ||
|---|---|---|---|---|---|
M1a | M1b | M1c | |||
Total | 505 | 74 | 296 | 134 | |
Age (years) | 0.426 | ||||
<48 | 259 (51.3) | 43 (58.1) | 149 (50.3) | 66 (49.3) | |
≥48 | 246 (48.7) | 31 (41.9) | 147 (49.7) | 68 (50.7) | |
Sex | 0.212 | ||||
Male | 427 (84.6) | 58 (78.4) | 256 (86.5) | 112 (83.6) | |
Female | 78 (15.4) | 16 (21.6) | 40 (13.5) | 22 (16.4) | |
UICC T category | 0.756 | ||||
T1 | 25 (5.0) | 3 (4.1) | 13 (4.4) | 8 (6.0) | |
T2 | 88 (17.4) | 14 (18.9) | 47 (15.9) | 27 (20.1) | |
T3 | 227 (45.0) | 29 (39.2) | 139 (47.0) | 59 (44.0) | |
T4 | 165 (32.7) | 28 (37.8) | 97 (32.8) | 40 (29.9) | |
UICC N category | 0.143 | ||||
N0 | 28 (5.5) | 7 (9.5) | 18 (6.1) | 3 (2.2) | |
N1 | 160 (31.7) | 25 (33.8) | 90 (30.4) | 44 (32.8) | |
N2 | 227 (45.0) | 35 (47.3) | 128 (43.2) | 64 (47.8) | |
N3 | 90 (17.8) | 7 (9.5) | 60 (20.3) | 23 (17.2) | |
KPS | 0.201b | ||||
≥80 | 476 (94.3) | 73 (98.6) | 276 (93.2) | 126 (94.0) | |
<80 | 29 (5.7) | 1 (1.4) | 20 (6.8) | 8 (6.0) | |
BMI | 0.699 | ||||
≥18.5 | 430 (85.1) | 65 (87.8) | 249 (84.1) | 115 (85.8) | |
<18.5 | 75 (14.9) | 9 (12.2) | 47 (15.9) | 19 (14.2) | |
Radiotherapy to primary tumor | <0.001 | ||||
No | 267 (52.9) | 22 (29.7) | 147 (49.7) | 98 (73.1) | |
Yes | 238 (47.1) | 52 (70.3) | 149 (50.3) | 36 (26.9) | |
Cycles of chemotherapy | 0.864 | ||||
≤ 4 | 273 (54.1) | 42 (56.8) | 159 (53.7) | 71 (53.0) | |
>4 | 232 (45.9) | 32 (43.2) | 137 (46.3) | 63 (47.0) | |