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Table 4 Surgical parameters and tumor regression after treatment in the TME and CCRT + TME groups

From: Surgery with versus without preoperative concurrent chemoradiotherapy for mid/low rectal cancer: an interim analysis of a prospective, randomized trial

Variable

TME group

CCRT + TME group

χ 2

P

Total (cases)

94

90

  

Sphincter preservation (cases [%])

 

0.036

0.849

 Yes

67 (71.3)

63 (70.0)

  

 No

27 (28.7)

27 (30.0)

  

Time of surgery (hours)

  

−1.106

0.269

 Median

3

3

  

 Range

2-6

2-10

  

Blood loss during surgery (mL)

 

−0.387

0.698

 Median

100

100

  

 Range

20-1,000

50-1,000

  

Hospital stay (days)

  

−0.540

0.589

 Median

9

9

  

 Range

6-33

6-98

  

Complications (cases [%])

    

 Urinary symptoms

0

2 (2.2)

 

0.238

 Anastomotic leakage

8 (8.5)

2 (2.2)

 

0.101

 Obstruction

1 (1.1)

1 (1.1)

 

1.000

 Temporary colostomy

0

3 (3.3)

 

0.115

 Wound infection

4 (4.3)

4 (4.4)

 

1.000

Tumor regression gradea (cases [%])

 4

NA

34 (37.8)

  

 3

NA

23 (25.6)

  

 2

NA

13 (14.4)

  

 1

NA

20 (22.2)

  

pTNM stage (cases [%])

  

3.202

0.202

 T1-2N0M0

16 (17.0)

17 (18.9)

  

 T3-4N0M0

39 (41.5)

21 (23.3)

  

 T1-4 N1-2 M0

39 (41.5)

20 (22.2)

  

pCR (cases [%])

NA

32 (35.6)

  
  1. pCR, pathologic complete response (ypT0N0); NA, not applicable. Other abbreviations as in Table 1. aThe Dworak regression grading system was used for tumor regression grading