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Table 4 Surgical parameters and tumor regression after treatment in the TME and CCRT + TME groups

From: Surgery with versus without preoperative concurrent chemoradiotherapy for mid/low rectal cancer: an interim analysis of a prospective, randomized trial

Variable TME group CCRT + TME group χ 2 P
Total (cases) 94 90   
Sphincter preservation (cases [%])   0.036 0.849
 Yes 67 (71.3) 63 (70.0)   
 No 27 (28.7) 27 (30.0)   
Time of surgery (hours)    −1.106 0.269
 Median 3 3   
 Range 2-6 2-10   
Blood loss during surgery (mL)   −0.387 0.698
 Median 100 100   
 Range 20-1,000 50-1,000   
Hospital stay (days)    −0.540 0.589
 Median 9 9   
 Range 6-33 6-98   
Complications (cases [%])     
 Urinary symptoms 0 2 (2.2)   0.238
 Anastomotic leakage 8 (8.5) 2 (2.2)   0.101
 Obstruction 1 (1.1) 1 (1.1)   1.000
 Temporary colostomy 0 3 (3.3)   0.115
 Wound infection 4 (4.3) 4 (4.4)   1.000
Tumor regression gradea (cases [%])
 4 NA 34 (37.8)   
 3 NA 23 (25.6)   
 2 NA 13 (14.4)   
 1 NA 20 (22.2)   
pTNM stage (cases [%])    3.202 0.202
 T1-2N0M0 16 (17.0) 17 (18.9)   
 T3-4N0M0 39 (41.5) 21 (23.3)   
 T1-4 N1-2 M0 39 (41.5) 20 (22.2)   
pCR (cases [%]) NA 32 (35.6)   
  1. pCR, pathologic complete response (ypT0N0); NA, not applicable. Other abbreviations as in Table 1. aThe Dworak regression grading system was used for tumor regression grading