Table 3 Adverse events during CCRT for the 90 patients in the CCRT + TME group (cases)
Adverse event | NCI-CTC grade | ||||
|---|---|---|---|---|---|
0 | 1 | 2 | 3 | 4 | |
Hematologic toxicity | |||||
 Anemia | 87 | 3 | 0 | 0 | 0 |
 Thrombocytopenia | 84 | 5 | 1 | 0 | 0 |
 Leukocytopenia | 74 | 5 | 8 | 3 | 0 |
Non-hematologic toxicity | |||||
 Diarrhea | 50 | 16 | 14 | 10 | 0 |
 Nausea/vomiting | 62 | 18 | 10 | 0 | 0 |
 Stomatitis | 80 | 10 | 0 | 0 | 0 |
 Abdominal pain | 78 | 8 | 4 | 0 | 0 |
 Proctitis | 58 | 16 | 16 | 0 | 0 |
Metabolic/laboratory abnormality | |||||
 AST/ALT elevation | 82 | 6 | 2 | 0 | 0 |
 Bilirubin elevation | 86 | 3 | 1 | 0 | 0 |
 Creatinine elevation | 89 | 1 | 0 | 0 | 0 |
Radiation-related toxicity | |||||
 Hand-foot skin reaction | 73 | 13 | 4 | 0 | 0 |
 Dermatitis | 66 | 16 | 8 | 0 | 0 |