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Table 3 Adverse events during CCRT for the 90 patients in the CCRT + TME group (cases)

From: Surgery with versus without preoperative concurrent chemoradiotherapy for mid/low rectal cancer: an interim analysis of a prospective, randomized trial

Adverse event NCI-CTC grade
0 1 2 3 4
Hematologic toxicity
 Anemia 87 3 0 0 0
 Thrombocytopenia 84 5 1 0 0
 Leukocytopenia 74 5 8 3 0
Non-hematologic toxicity
 Diarrhea 50 16 14 10 0
 Nausea/vomiting 62 18 10 0 0
 Stomatitis 80 10 0 0 0
 Abdominal pain 78 8 4 0 0
 Proctitis 58 16 16 0 0
Metabolic/laboratory abnormality
 AST/ALT elevation 82 6 2 0 0
 Bilirubin elevation 86 3 1 0 0
 Creatinine elevation 89 1 0 0 0
Radiation-related toxicity
 Hand-foot skin reaction 73 13 4 0 0
 Dermatitis 66 16 8 0 0
  1. AST, aspirate aminotransferase; ALT, alanine aminotransferase; NCI-CTC, National Cancer Institute Common Toxicity Criteria