From: TLR3 gene polymorphisms in cancer: a systematic review and meta-analysis
TLR3 SNP | Location | Association(s) with tumor(s) |
---|---|---|
rs10025405 | 3′-near gene | Breast cancer, associated [20] |
rs11721827 | Intron 1 | Nasopharyngeal carcinoma, associated [4] |
Colorectal cancer, associated [17] | ||
rs11730143 | Intron 1 | Melanoma, not associated [16] |
rs13126816 | Intron 1 | Melanoma, not associated [16] |
rs3775290 | Exon 4 | Nasopharyngeal carcinoma, not associated [4] |
Bladder cancer, not associated [5] | ||
Prostate cancer, not associated [6] | ||
Cervical cancer, not associated [7] | ||
Breast cancer, not associated [8] | ||
Cervical cancer, associated [22] | ||
rs3775291 | Exon 4, L412F | Nasopharyngeal carcinoma, not associated [4] |
Hepatocellular carcinoma, associated [9] | ||
Breast cancer, not associated [15] | ||
Melanoma, not associated [16] | ||
Colorectal cancer, not associated [17] | ||
Breast cancer, not associated [18] | ||
Oral cancer, associated [19] | ||
Nasopharyngeal carcinoma, associated [21] | ||
rs3775292 | Intron 3 | Melanoma, not associated [16] |
Colorectal cancer, associated [17] | ||
Breast cancer, not associated [18] | ||
rs5743305 | 5′-near gene | Hepatocellular carcinoma, not associated [9] |
Colorectal cancer, not associated [17] | ||
rs5743312 | Intron 3 | Nasopharyngeal carcinoma, not associated [4] |
Melanoma, not associated [16] | ||
Oral cancer, associated with survival [19] | ||
rs7657186 | Intron 1 | Melanoma, not associated [16] |
Breast cancer, not associated [20] | ||
rs7668666 | Intron 3 | Melanoma, not associated [16] |