Fig. 2

The linkage disequilibrium plot of TLR3 gene polymorphisms found in individuals of different ethnicities, expanding 20 kb from 5′ to 3′ each (downloaded from the HapMap database). a, European; b, Chinese Han; c, Japanese; d, African. Different SNP distributions arise in response to differences in ethnicity. Therefore, differences in ethnicity should be considered when designing the study. Furthermore, some TLR3 SNPs might be in linkage disequilibrium, suggesting that a haplotype study may be more effective for predicting or screening susceptible populations