Table 3 Comparison of clinical and pathologic characteristics between HCAs and HCAs with malignant transformation
From: Hepatocellular adenoma with malignant transformation in male patients with non-cirrhotic livers
Variable | HCA group ( n = 17) | HCC group ( n = 5) | Statistic | P value |
|---|---|---|---|---|
Age (years) | t = 0.935 | 0.361 | ||
Mean | 33 | 46 | ||
Range | 27–71 | 40–53 | ||
Sex (cases) | 0.040 | |||
Male | 7 | 5 | ||
Female | 10 | 0 | ||
Alcohol intake (cases) | 0.548 | |||
Yes | 3 | 2 | ||
No | 14 | 3 | ||
Overweight (cases) | 0.274 | |||
Yes (BMI ≥ 25 kg/m2) | 4 | 3 | ||
No (BMI < 25 kg/m2) | 13 | 2 | ||
HBsAg (cases) | 1.000 | |||
Positive | 1 | 0 | ||
Negative | 16 | 5 | ||
AFP (ng/mL) | 1.90 (1.51, 2.99) | 4.37 (2.63, 6.52) | U = 9 | 0.009 |
ALT (U/L) | 22 (13, 27) | 31 (18, 40) | U = 26 | 0.195 |
GGT (U/L) | 23 (13, 44) | 62 (29, 122) | U = 18 | 0.055 |
TBIL (μmol/L) | 8.7 (5.8, 9.8) | 12.4 (8.3, 18.1) | U = 22 | 0.108 |
ALB (g/L) | 41.3 ± 4.1 | 42.4 ± 2.6 | t = 0.571 | 0.574 |
PLT (×109/L) | 187.2 ± 40.99 | 227.6 ± 49.04 | t = 1.857 | 0.078 |
INR | 1.00 (0.93, 1.03) | 0.94 (0.91, 0.98) | U = 27.5 | 0.238 |
Number of tumors (cases) | 1.000 | |||
1 | 14 | 5 | ||
≥2 | 3 | 0 | ||
Tumor diameter (cm) | 6.5 (3.5, 9.0) | 10.0 (2.3, 13.0) | U = 37 | 0.666 |