Association of the Asp312Asn and Lys751Gln polymorphisms in the XPD gene with the risk of non-Hodgkin’s lymphoma: evidence from a meta-analysis

Table 1 Characteristics of the included case-control studies reporting on the association of the Asp312Asn or Lys751Gln polymorphism in the xeroderma pigmentosum complementation group D ( XPD ) gene with the risk of non-Hodgkin’s lymphoma (NHL)

Reference	Year	Country	Ethnicity	Source of controls	Genotyping method	Cases				Controls				MAF	HWE
Asp312Asn (rs1799793 G > A) polymorphism						GG	GA	AA	All	GG	GA	AA	All
Hill et al. [13]	2006	USA	Mixed	PB	TaqMan	355	306	86	747	307	273	56	636	0.303	0.671
Shen et al. [14]	2006	USA	Mixed	PB	TaqMan	199	189	57	445	226	238	70	534	0.354	0.557
Smedby et al. [15]	2006	Denmark and Sweden	Caucasian	PB	Mass spectrometry	167	211	50	428	262	255	85	602	0.353	0.075
Shen et al. [16]	2007	Australia	Caucasian	PB	TaqMan	272	210	72	554	238	211	52	501	0.314	0.606
Song et al. [17]	2008	China	Asian	HB	PCR-RFLP	256	47	4	307	265	35	3	303	0.068	0.142
Worrillow et al. [18]	2009	UK	Caucasian	PB	TaqMan	270	265	79	614	316	335	79	730	0.338	0.483
Lys751Gln (rs13181 A > C) polymorphism						AA	AC	CC	All	AA	AC	CC	All
Hill et al. [13]	2006	USA	Mixed	PB	TaqMan	320	333	93	746	278	295	66	639	0.334	0.343
Shen et al. [14]	2006	USA	Mixed	PB	TaqMan	203	189	64	456	207	256	67	530	0.368	0.375
Smedby et al. [15]	2006	Denmark and Sweden	Caucasian	PB	Mass spectrometry	159	209	56	424	231	254	106	591	0.394	0.015
Shen et al. [16]	2007	Australia	Caucasian	PB	TaqMan	239	229	74	542	210	211	57	478	0.340	0.720
Song et al. [17]	2008	China	Asian	HB	PCR-RFLP	261	43	5	309	270	32	3	305	0.062	0.075
Worrillow et al. [18]	2009	UK	Caucasian	PB	TaqMan	286	329	85	700	294	378	107	779	0.380	0.405
Yang et al. [19]	2009	China	Asian	HB	Mass Array	64	7	1	72	304	48	2	354	0.073	0.944

MAF, minor allele frequency; HWE, Hardy–Weinberg equilibrium; USA, the United States of America; UK, the United Kingdom; PB, population-based; HB, hospital-based; PCR-RFLP, polymerase chain reaction-restriction fragment length polymorphism.

ISSN: 2523-3548